Zhonghua Yi Xue Za Zhi
[The impact of KIT and other concomitant gene mutations on the prognoses of patients with core-binding factor acute myeloid leukemia].
Wang F, Wang W, Liu M, Zhang Y, Chen X, Yuan LL, Ma XL, Nie DJ, Wang MY, Zhang Y, Zhang W, Liu MY, Liu HX
Objective: To study the impact of KIT and other concomitant gene mutations on the prognoses of patients with core-binding factor acute myeloid leukemi ...
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Source: PubMed
Biomed. Pharmacother.
Grape seed proanthocyanidin extract reverses multidrug resistance in HL-60/ADR cells via inhibition of the PI3K/Akt signaling pathway.
Lin KN, Jiang YL, Zhang SG, Huang SY, Li H
Multidrug resistance (MDR) is a great challenge and obstacle in cancer treatment. It is a common problem in the treatment of acute myeloid leukemia (A ...
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Source: PubMed
Biomed. Pharmacother.
Decitabine and all-trans retinoic acid synergistically exhibit cytotoxicity against elderly AML patients via miR-34a/MYCN axis.
Cao Y, Liu Y, Shang L, Wei W, Shen Y, Gu Q, Xie X, Dong W, Lin Y, Yue Y, Wang F, Gu W
This study aimed to investigate the efficacy and mechanism of decitabine (DAC) and all-trans retinoic acid (ATRA) in elderly acute myeloid leukemia (A ...
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Source: PubMed
Cytokine
Serum levels of selected cytokines and soluble adhesion molecules in acute myeloid leukemia: Soluble receptor for interleukin-2 predicts overall survival.
Kupsa T, Vanek J, Zak P, Jebavy L, Horacek JM
Acute myeloid leukemia (AML) cells are highly resistant to chemotherapeutic drugs. Cytokines and adhesion molecules may contribute to this resistance ...
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Source: PubMed
Methods Mol. Biol.
Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy.
Iversen PO, Sioud M
When introduced into endosomes via cationic lipids, certain small interfering RNA (siRNA) sequences activate the interferon signaling pathways in immu ...
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Source: PubMed
