Last Updated on Sep 13, 2016

Complications

Heart failure is the leading cause of death in infective endocarditis.

Infective endocarditis is a fatal disease if left untreated. Heart failure is the leading cause of death in infective endocarditis. This is due to the damage caused to valves. 40-60% of autopsies reveal heart attack to be reason of death.

Local damage to the coverings of the heart (endocardium or myocardium) is a dreaded complication. Complications due to emboli (already described) are rarer in the antibiotic era.

Aggressive vegetations lead to perforations and fistula in the valves and walls of the heart.

Occlusion of vessels lead to infarction (death of tissues due to lack of blood supply) in vital organs like kidney, spleen and the brain

Seeding of bacteria from the site of infection to distant sites (metastasis) can occur. The bones may get infected, for example, leading to osteomyelitis.

The circulation of immune complexes may get deposited in the kidney. Immune mediated joint pain (arthritis) is not uncommon.

References:

  1. Cecil Medicine, 23rd Ed.
  2. The Merck Manual, 18th Ed.

Comments

navyalikitha Thursday, June 28, 2012

MAY I KNOW THE RECENT ADVANCES IN THERAPY OF ENDOCARDITIS EXACTLY?? I MEAN ANY NEW DRUGS RECENTLY INVENTED etc...

Jams34 Saturday, February 11, 2012

WHAT ARE Z PROBLEMS IF U SENT US UR WEB SITE...SINCE WE WANT SOME IDEAS IN RELATION 2 HEALTH ...,I AM St. of health ...from Ethiopia...

aravind007 Saturday, February 19, 2011

why the rate of development of the disease can happen either quickly or slowly depending on the type of germ that causes it and the medical history of the patient?

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