Adverse Effects Insomnia or disturbed sleep: This is caused at the onset of the hot flash which happens during the night. The other reason could also be social implications faced by postmenopausal women. The psychological trauma: Many women also experience symptoms like irritability, depression, and anxiety. These are accompanied with hot flashes and affect many post menopausal women. Hot Flash - References: Avantina Sharma, Textbook of Food Science and Technology, International Book distributor (IBDC) publishers, India. Albertazzi P et al. The effect of dietary soy supplementation on hot flushes. Obstetrics and Gynecology 1998;91: 6-11 Charles L Loprinzi et al. Venlafaxine in management of hot flushes in survivors of breast cancer: a randomized controlled trial. The Lancet. Volume 356 Page 2059 Jeri AR. The effect of isoflavones phyto-estrogens in relieving hot flushes in Peruvian postmenopausal women. Paper presented at: 9th International Menopause Society World Congress on the Menopause; October 20, 1999; Yokahama, Japan. Vasomotor symptom relief by soy isoflavone extract tablets in postmenopausal women: a multicenter, double blind, randomized, placebo-controlled study. Menopause. 2000 Jul-Aug;7(4):236-42. Published on Oct 17, 2014Last Updated on Mar 21, 2018