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Glomerulonephritis - Mechanism of Damage to the Nephrons: Frequently Asked Questions

Last Updated on Feb 29, 2016
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Frequently Asked Questions

1. Which doctor should I see if I am diagnosed with Glomerulonephritis?

A Nephrologist should be consulted for glomerulonephritis.

2. What is the most common type of Glomerulonephritis among children and what is the prognosis?

In children, glomerulonephritis occurs in the form of minimal change nephropathy. The kidney tissue will look normal after a biopsy with minimal changes, but the symptoms of glomerulonephritis will still be present.

The symptoms include dark brown colored urine, fatigue, weight loss, breathing difficulty, rashes over the buttocks and legs, fluid build up in the tissues and development of pale color on the face.

3. I have Focal Segmental Glomerulosclerosis (FSGS) and need a transplantation. will my disease come back?

Glomerulosclerosis is a chronic condition and the scarred glomeruli cannot be restored to their original condition. Administering the appropriate treatment will aid in delaying the progression of the disease, which also depends on the age of the patient, the stage of the disease and the ability of the patient to cope with treatment.

As time and disease progress, some patients may require a kidney transplant. Though the kidney transplant is necessary and will help the condition, there exists a chance of glomerulosclerosis reappearing even after the transplant.

4. I always have some trace of blood in the urine when I am running and my doctor says it is likely to be IgA Nephropathy, what should I do?

IgA nephropathy is caused due to the deposition of IgA antibody in the kidney and it may even take 10 to 20 years before the symptoms are expressed.

After strenuous exercise like running, red blood cells may be expelled in the urine, giving urine a tea color or a cola color. Make an appointment with the doctor. Also look for other symptoms like swollen feet and hands. If there is excessive bleeding, it could be a more severe infection or condition requiring immediate medical help.

5. How does the doctor know the type of glomerulonephritis?

The symptoms are the first clue about the underlying disease which is later confirmed by performing a blood test. In most instances, doctors may require a kidney biopsy to confirm the diagnosis and to study the extent of damage to the kidney.

6. What is kidney biopsy and how is it done?

Kidney biopsy involves taking a sample of the kidney tissue to be studied under a special microscope for a detailed study about the state of the kidney. This provides vital clues which can be used for effective treatment. There are two ways of obtaining a kidney biopsy.

A. Open surgery: A small piece of kidney tissue is removed during a surgical procedure that involves making an incision.

B. Percutaneous: A needle is injected into the skin above the kidneys and is used to obtain a kidney biopsy, usually guided by ultrasound.

7. What are the complications of kidney biopsy?

Complications as a result of procedures performed to take a kidney biopsy are rare. In very rare cases, if there is excessive bleeding, a blood transfusion may be required or a blood vessel may be damaged necessitating an additional surgical procedure to treat the damaged vessel.

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i was diagnosed with mpgn type 2 at 4 yrs old... it all started with a persistant cold. My mom always thought i was pale but, she had no idea until she found me lethargic on the floor.. my blood pressure was sky high. my urine was black. my 14 yr treatment consisted of aggressive doses of prednisone and blood pressure medication. i also give all the credit in the world to the doctors and staff at the Motts childrens hospital in ann arbor michigan.

Tamara Harchanko

my stepmom has minimal change disease- she also has rhem.arthritis- last week relapsed into MCD- her ankles are swolen to painful- Is there anybody who knows what foods are for her to eat???? She also suffers from celiac and is under 100 lbs- Please help!!


to whom it may concern... I am a 20 year old servivor of MPGN. i was diagnosed at 4 and have now been in remission for 4 years. ive never had a transplant, and although i was very close to it ive never been on dialysis.


Hi bree. Glad to hear you are a survivor of MPGN. I am from ireland and my brothers little girl took this disease 9 weeks ago. She is on dialayis ever day and we are very concerned for her. I would be greatly obliged and grateful to hear the full story of your experiences and any advice you could offer me. Thankyou for you time and take care, colin


it all started with a persistant cold.. after about two months of an upper respertory infection my mom found me lethargic on the floor.. my urine was black it was mpgn type 2.


Hi Bree! My daughter was diagnosed with MPGN type 1 in 2004, she continues to have problems with anemia, seems to be getting worse. Just wondering if you had the same problem?

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