3. Are radiotherapy and chemotherapy applicable to all age groups?Multisession radiotherapy and intensity modulated radiation therapy (IMRT) are not recommended for young children as their brains are still in developmental stages and highly susceptible to long-term permanent developmental damage. Whereas, chemotherapy may be used as a primary therapy in young children or as adjuvant therapy (for example, after the tumor has been surgically removed).
4. Why it is difficult to treat glioblastoma?This is due to several reasons as below:
- Tumor cells are resistant to conventional therapies.
- Conventional therapy can cause damage to the brain.
- Brain has a very limited capacity for its repair.