AZFb and candidate genes:
AZFb locus spans about 1.5 Mb of the Y chromosome.
Two important candidate gene families that have been mapped on the AZFb locus are EIF1AY (translation initiation factor 1 A, Y isoform) and RBMY (
EIF1AY encodes a ubiquitously expressed translation initiation factor. However it also possesses abundant testis-specific transcripts.
RBMY is a multicopy
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Dr. Reeja Tharu. (2016, November 04). Genetics of Male Infertility - Y-Chromosome Microdeletions. Medindia. Retrieved on May 26, 2022 from https://www.medindia.net/patients/patientinfo/gentmaleinfertility_micro3.htm.
Dr. Reeja Tharu. "Genetics of Male Infertility - Y-Chromosome Microdeletions". Medindia. May 26, 2022. <https://www.medindia.net/patients/patientinfo/gentmaleinfertility_micro3.htm>.
Dr. Reeja Tharu. "Genetics of Male Infertility - Y-Chromosome Microdeletions". Medindia. https://www.medindia.net/patients/patientinfo/gentmaleinfertility_micro3.htm. (accessed May 26, 2022).
Dr. Reeja Tharu. 2021. Genetics of Male Infertility - Y-Chromosome Microdeletions. Medindia, viewed May 26, 2022, https://www.medindia.net/patients/patientinfo/gentmaleinfertility_micro3.htm.