Male Infertility - Choromosomal Abnormalities

Dr. Reeja Tharu
Medically Reviewed by The Medindia Medical Review Team  on Nov 04, 2016
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Chromosomal Abnormalities

Among men with azoospermia, the frequency of chromosomal abnormalities is estimated to be around 16%. Of these males 13% are found to have Klinefelter’s syndrome and the remaining 3% have other chromosomal aberrations, such as ring Y chromosome and translocations.

5-6% of oligozoospermic men have karyotype anomalies which are mostly autosomal robertsonian and reciprocal translocations. In a recent study, sperm from men with extremely severe oligoasthenoteratozoospermia were found to have significantly higher frequency of aneuploidy and diploidy.

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