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Male Infertility - Choromosomal Abnormalities

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Chromosomal Abnormalities

Among men with azoospermia, the frequency†of†chromosomal abnormalities is estimated to be around 16%. Of these males†13% are found to have Klinefelterís syndrome and the remaining†3%†have†other chromosomal aberrations,†such†as†ring Y†chromosome†and†translocations.

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5-6% of oligozoospermic men have karyotype anomalies which are mostly autosomal robertsonian and reciprocal translocations.†In a recent study, sperm from men with extremely severe oligoasthenoteratozoospermia were found to have significantly higher frequency of aneuploidy and diploidy.

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