Creator: Dr. Reeja Tharu
Keywords: genetic counseling, genes, Huntington's disease, genetic disorders, infertility,miscarriage, Down's syndrome, DNA, alpha-fetoprotein, pedigree, cytogenic diagnosis, molecular diagnosis, polymerase chain reaction, mendelian inheritance, autosomal recessive,autosomal dominant,X-linked recessive, X-linked dominant,non-mendelian inheritance,polygenic defects, multifactorial inhertance

Written by Dr. Reeja Tharu, M.Phil.,Ph.D
Medically Reviewed by The Medindia Medical Review Team on Sep 18, 2020

Estimation of Risks of Genetic Counselling

X - LINKED RECESSIVE

The Transmission in this type of inheritance is linked to the X or Sex chromosomes.

case #1

case #2

case #3

Example

X - LINKED Lesch - Nyhan Syndrome.

Features

Males more commonly affected than females

Father to son transmission it is Not possible

Females - more likely to remain carriers and can transmit affected trait to 50% of her sons

Published on Jan 25, 2016
Last Updated on Sep 18, 2020

Comments

nagarasan Monday, December 28, 2009

I am Nagarasan in India. I am affected with congental myotonia from childhood. What genetic counseling is there for curing this in gene theraphy.

@Guest Thursday, March 5, 2015

Gene therapy is still not an approved therapy in human beings.

However, limited symptomatic treatment may be available.

Also, if you have the genetic confirmation of the disorder, you can potentially prevent the future generation from inheriting the same condition.

Regards,

Dr. Risha Nahar
Genetic Consultant

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