Last Updated on Aug 12, 2014

Symptoms and Signs of Epidermolysis Bullosa

Symptoms of Epidermolysis Bullosa are usually due to blisters.

People born with epidermolysis bullosa have a very fragile skin that develops blisters in response to minor injuries. Rubbing the skin or applying pressure generates blisters and painful sores.

Development of blisters in or around the mouth and throat causes feeding problems. Swallowing is difficult.

Other symptoms and signs include:

  • Hair loss (Alopecia)
  • Dental problems like tooth decay Nail problems like nail loss and deformed nails Tiny white bumps or pimples called milia on the skin

Babies born with EB may present with hoarse cry, cough, or breathing problems.


  1. A.D.A.M Medical Encyclopedia
  2. Vesicular and bullous diseases. In: Habif TP, ed. Clinical Dermatology. 5th ed. Philadelphia, Pa: Mosby Elsevier;2009;chap 16.
  3. Morelli JG. Vesiculobullous disorders. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 653.


Navjit Tuesday, October 15, 2013

Is there any treatment for Epidermolysis bullosa [Junctional Variety](Herlitz Variant). Acctually we got one baby before and he got this problem . He was died when he was 11yrs old. We also got one daught she is 7 yrs old and she dont hv any problem she is ok . Now we got new baby Boy . But he got same eb problem. So i want to know if there is any treatment for this. Please reply my post thanks

dr.sankararao Monday, February 25, 2013

i am having a mother with 2 siblings are died of epidermolisis bullosa now the patient is pregnent can any thing can be done to this poor lady pls respond.

dandie1109 Tuesday, February 7, 2012

As U understand, there is NO CURE of any kind! What information indicated a partial cure is available as stated in this article?

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