About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Drugs Causing Low Sodium Levels / Hyponatremia
Advertisement

Drugs Causing Low Blood Sodium Levels / Hyponatremia

Last Updated on Nov 21, 2019
Font : A-A+

About

Hyponatremia is a condition where plasma sodium level falls to less than 135 mmol/L.

Advertisement

The body maintains a careful balance of electrolytes like sodium, potassium and chloride within the cells as well as in fluid outside the cells like blood and body fluids. Sodium is necessary to carry out some important functions like maintaining blood pressure. It also helps to maintain the function of nerves and muscles. Sodium enters the body through food and fluid intake. The common salt or table salt contains sodium chloride and it is used not only for cooking but also in preservatives. The same sodium chloride also is the reason for the salinity of our oceans. Excess sodium is excreted by the kidneys via the urine. Sodium levels in the plasma are normally maintained at a level of between 135 to 145 mmol/L.(1 Trusted Source
Hyponatremia: A Practical Approach

Go to source
)

The condition in which plasma level of sodium falls to below 135 mmol/L is called hyponatremia. Hyponatremia causes movement of excess water in the cells, causing them to swell. The cells of the brain in particular are unable to cope up with this swelling since they are confined within the bones of the skull. Thus, many of the symptoms caused by hyponatremia, especially severe cases, are related to the brain.(2 Trusted Source
Effects of Hyponatremia on the Brain

Go to source
)

Advertisement

When taking medication we must remember that some of the drugs cause hyponatremia as a side effect. Many among these bring about this effect by resulting in a condition called SIADH or Syndrome of Inappropriate Secretion of ADH. ADH (antidiuretic hormone) or vasopressin is a hormone secreted by a small gland near the brain called the pituitary. It plays an important role in water absorption from the kidneys and stimulates thirst. Thus, in conditions of dehydration, by increasing water absorption from the urine and stimulating thirst, it helps to maintain the water content of the body.

SIADH is a condition where the control of ADH secretion is lost and it is secreted independent of the need to conserve water. This results in water retention and subsequent dilution of sodium levels, leading to hyponatremia.

Advertisement

Symptoms of hyponatremia may be mild like:

Nausea, vomiting, headache, and muscle cramps, or Symptoms may be serious like alteration in mental status including confusion, seizures and coma.

Symptoms of Hyponatremia

If hyponatremia is diagnosed, a careful history should be taken from the patients or their caregivers to find out if the patients are taking any medications that could result in hyponatremia. Stopping the medication usually helps to solve the problem.(3 Trusted Source
Hyponatremia

Go to source
)

References:

  1. Hyponatremia: A Practical Approach - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192979/)
  2. Effects of Hyponatremia on the Brain - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470176/)
  3. Hyponatremia - (https://www.kidney.org/atoz/content/hyponatremia)
  4. Management of Hyponatremia - (https://www.aafp.org/afp/2004/0515/p2387.html)
  5. A Review of Drug-induced Hyponatremia - (https://www.ncbi.nlm.nih.gov/pubmed/18468754)

Latest Publications and Research on Drugs Causing Low Blood Sodium Levels / Hyponatremia

Citations   close

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Dr. Simi Paknikar. (2019, November 21). Drugs Causing Low Blood Sodium Levels / Hyponatremia. Medindia. Retrieved on May 16, 2022 from https://www.medindia.net/patients/patientinfo/drugs-causing-low-sodium-levels-hyponatremia.htm.

  • MLA

    Dr. Simi Paknikar. "Drugs Causing Low Blood Sodium Levels / Hyponatremia". Medindia. May 16, 2022. <https://www.medindia.net/patients/patientinfo/drugs-causing-low-sodium-levels-hyponatremia.htm>.

  • Chicago

    Dr. Simi Paknikar. "Drugs Causing Low Blood Sodium Levels / Hyponatremia". Medindia. https://www.medindia.net/patients/patientinfo/drugs-causing-low-sodium-levels-hyponatremia.htm. (accessed May 16, 2022).

  • Harvard

    Dr. Simi Paknikar. 2021. Drugs Causing Low Blood Sodium Levels / Hyponatremia. Medindia, viewed May 16, 2022, https://www.medindia.net/patients/patientinfo/drugs-causing-low-sodium-levels-hyponatremia.htm.


Do you wish to consult a Pharmacologist for your problem? Ask your question

View All

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.

Comments

Libby

How do you know your sodium levels are too low or too high? Are the symptoms different?

Advertisement
Health Topics A - Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z



    Advertisement
    What's New on Medindia
    World Hypertension Day 2022 - Measure Blood Pressure Accurately, Control It, Live Longer!
    Drinking This Popular Beverage May Drop Dementia Risk
    Worst Mistakes Parents Make When Talking to Kids
    View all
    Advertisement

    Medindia Newsletters Subscribe to our Free Newsletters!
    Terms & Conditions and Privacy Policy.

    Most Popular on Medindia

    A-Z Drug Brands in India Blood - Sugar Chart Color Blindness Calculator Noscaphene (Noscapine) Blood Pressure Calculator Sanatogen Iron Intake Calculator Loram (2 mg) (Lorazepam) Nutam (400mg) (Piracetam) Drug Side Effects Calculator

    Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

    © All Rights Reserved 1997 - 2022

    This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use