Last Updated on Jul 06, 2018

Treatment of Deep Vein Thrombosis (DVT)

Deep vein thrombosis often requires anticoagulation or blood thinning therapy. Warfarin (Coumadin) is the drug of choice for anti-coagulation.

Superficial blood clots are cured with warm compresses, leg compression, and anti-inflammatory medications such as ibuprofen. Deep vein thrombosis often requires anticoagulation or blood thinning treatment. Anticoagulation prevents further growth and propogation of the blood clot. It also prevents the development of the deadly complication called pulmonary embolism.

Warfarin (Coumadin) is the drug of choice for anti-coagulation. The drug takes some time to initiate its action. Hence a drug called low molecular weight heparin (LMWH, e.g. Enoxaparin) injection is administered at the same time when warfarin tablets are started. It is referred to as a ‘bridge therapy’ that acts when warfarin is getting ready for action. Patients receiving this therapy will have to undergo routine blood tests (prothrombin time or INR (International Normalized Ratio). This is very important. Not all patients are fit for anti coagulant therapy. Bleeding in the brain, major trauma, or recent significant surgery are contra indications.

The technique called thrombolysis or breaking of the clot does not have convincing proofs of efficacy.

Vena Caval Filter: A filter is placed in the major vessel called inferior vena cava. It helps in preventing clots from reaching the heart and lung. The filter is not devoid of complications though.

Surgery is a rare modality used in the management of DVT. People who cannot take anti-coagulation therapy or who developed recurrent blood clots while on anti-coagulant medications may benefit from surgery.


  1. Sabiston Textbook of Surgery, 18th ed.
  2. Bailey & Love Short Practice of Surgery, 25th ed.


Nurgul Sunday, October 14, 2012

Does anybody know where is the best place for my mom to have a surgery of deep vein thrombosis? Doctor said she must have an operation but he said in our country is not the best place to do it... He has advised Israel, Russia... what do you think?

josgreg Saturday, March 19, 2011

The article provided a nice graphical view on the disease which was of the more specific on the topic. Diagnosis of deep vein thrombosis To diagnose this condition, you may have to undergo the following tests in an infirmary: >A blood test which is named as D-Dimer is usually done to measure a substance which is responsible for blood clots to break down. If you have negative reading in this test, it tells that you have deep vein thrombosis.

Most Popular on Medindia