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Chronic Granulomatous Disease (CGD) - Frequently Asked Questions


Q: Which specialist doctor should be consulted for treatment and follow up of chronic granulomatous disease?

A: Consult a Hematologist or a General Physician. For biopsy a General Surgeon may need to be involved.

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Q: Do CGD ever affect girls?

A: The most common genetic type of CGD affects only boys. There are however some genetic types that affect girls.

Q: Which races are more susceptible to CGD?

A: No racial predilection is known.

Q: What are the complications of CGD?

A: Kell antigens form a group of antigens on the human red blood cell surface. Gene deletions make patients with CGD sensitised to Kell antigens after blood transfusions, i.e. antibodies are produced against these antigens. This leads to complications after subsequent transfusions. Hence it is important to examine the Kell-antigen status in patients.

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