Under normal conditions, our body resorts to its own mechanism to cope with bleeding through a process called hemostasis. During this process the blood vessels constrict to decrease blood flow and platelets in the blood accumulate to form a plug. This is then stabilized by a film of fibrin that forms a barrier. This barrier remains in place till the injury is fully healed.
The process of clot formation, involving a range of clotting factors, occurs sequentially in a coagulation ‘cascade’. The clot is dissolved (fibrinolysis) once the wound is healed.
In people with bleeding disorders, the clotting process is impaired and this results in spontaneous bleeding. If a component that aids in clotting is missing, deficient or is dysfunctional then it results in excessive bleeding.
Bleeding conditions do not have a permanent cure. They can, however, be managed.
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