About Careers MedBlog Contact us
Medindia LOGIN REGISTER
Advertisement

Infections and Birth Defects

Last Updated on Aug 14, 2017
Font : A-A+

Infections and Birth Defects

InfectionCausative MicroorganismClinical featuresPrevention
Rubella / German MeaslesVirus, potent teratogenRisk of infection during the first trimester is 20%. Leads to congenital Rubella Syndrome- Cataract, cardiac defects, and deafness. Less commonly - Chorioretinitis, glaucoma, microphthalmia (Small, abnormal eyes), and tooth defects.Rubella vaccine is usually administered to girls aged 10-14 years. It is recommended for women of child-bearing age who are found to be seronegative, Seronegative pregnant women should be vaccinated in the early postpartum period. Pregnancy should be avoided for at least one moth after vaccination.
Cytomegalovirus infectionVirus, cytomegalovirus (CMV)Most common viral infection the human fetuses. Spontaneous abortion in first trimester, intrauterine growth retardation (IUGR), microphthalmia, chorioretinitis, blindness, microcephaly (very small head), mental retardation, cerebral palsy, hepatosplenomegaly (enlargement of the liver and spleen).Practice good personal hygiene; handwashing with soap and water is effective. Care should be taken while handling children and diapers.
Herpes Simplex infectionHerpes Simplex virus (HSV). Infection commonly occurs during delivery.Spontaneous abortion, premature delivery, skin related defects, microcephaly, microphthalmia, spasticity, retinal dysplasia (detachment of the retina), and mental retardation.Avoiding contact with someone who has an active herpes infection can prevent the disease during pregnancy. Aseptic precautions during delivery are necessary.
Chicken PoxVaricella zoster virusScarring of fetal skin, muscular atrophy (reduction in muscle size), rudimentary digits/ fingers and mental retardation.Chicken Pox vaccine
HIV infectionHuman Immuno Deficiency VirusGrowth failure, Craniofacial defects (defects of the face and head).General preventive measures for HIV also hold good during pregnancy. Do not share injections, needles or syringes with anybody else. Do not breast feed your baby if you have an HIV infection. Talk to your doctor regarding the options available if you are already infected with HIV.
ToxoplasmosisToxoplasma gondii, eating raw or poorly cooked meat (pork/lamb).Changes in the brain and eyes, microcephaly, microphthalmia, hydrocephaly (excessive fluid/ CSF accumulation in the brain).Avoiding contact with pet animals (cat, dog, rabbit) and eating safe, properly cooked meat.
SyphilisTreponema pallidum can be infected at any stage of pregnancy.Primary infection: Congenital deafness, abnormal teeth, bones, hydrocephalus, mental retardation. Secondary infection: Destructive lesions of the palate and nasal septum, dental abnormalities (Hutchinson’s teeth), abnormal facial features. 
Viral InfectionHuman parvovirus B19Eye defects, degenerative changes in fetal tissues.No vaccination available. Practice of safe hygienic habits can reduce the risk.
EncephalitisVenezuelan equine encephalitis virusMicrocephaly, microphthalmia, cerebral agenesis, CNS necrosis, hydrocephalus.
Advertisement

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Dr. Reeja Tharu. (2017, August 14). Infections and Birth Defects. Medindia. Retrieved on Mar 25, 2023 from https://www.medindia.net/patients/patientinfo/birthdefects_infections_birth.htm.

  • MLA

    Dr. Reeja Tharu. "Infections and Birth Defects". Medindia. Mar 25, 2023. <https://www.medindia.net/patients/patientinfo/birthdefects_infections_birth.htm>.

  • Chicago

    Dr. Reeja Tharu. "Infections and Birth Defects". Medindia. https://www.medindia.net/patients/patientinfo/birthdefects_infections_birth.htm. (accessed Mar 25, 2023).

  • Harvard

    Dr. Reeja Tharu. 2021. Infections and Birth Defects. Medindia, viewed Mar 25, 2023, https://www.medindia.net/patients/patientinfo/birthdefects_infections_birth.htm.


Do you wish to consult a Pediatrician for your problem? Ask your question

Dr. Atish Bakane
Dr. Atish Bakane
MBBS, DCh, DNB, FNB
12 years experience
Dr. Adarsh Prabhakar Bagali
Dr. Adarsh Prabhakar  Bagali
MBBS, MD, NICU
5 years experience
Dr. Nandita Gautam
Dr. Nandita Gautam
MBBS, MD
4 years experience
Dr. Vishal Parmar
Dr. Vishal Parmar
MBBS, DCH, MRCPCH, Fellow In Neonatal Medicine
10 years experience
Shri Hari Child Clinic and Vaccination Centre, Borivali East, Mumbai
+ 1 more
View All

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.

Advertisement
Recommended Reading
Benefits of Registration
Advertisement
Health Topics A - Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
Drugs for Birth Defects - Infections
Spiramycin
What's New on Medindia
Quiz on Clinical Trials
Health Benefits of Drinking Green Coffee
World Tuberculosis Day: Understanding the Global Impact of Tuberculosis
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.
This site uses cookies to deliver our services.By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use  Ok, Got it. Close