Treatment of Biliary Cirrhosis
Treatment of biliary cirrhosis includes:
- Ursodeoxycholic acid (UDCA) is used for the treatment of PCA. UDCA appears to improve survival and slow the liver damage, thus delaying the requirement for liver transplantation.
- Corticosteroids are effective in PCA, however, their harmful effects may outweigh their benefits, and hence they are not used in the treatment of PCA.
- Cholestyramine, rifampicin, naloxone and plasmapheresis (procedure used to purify the blood) are useful to treat itching.
- Calcium and vitamin D supplementation may help to reduce osteoporosis or bone thinning.
- Liver transplantation is necessary in cases of severe liver damage.
- Simon Hohenester & Ronald P. J. Oude-Elferink & Ulrich Beuers. Primary biliary cirrhosis. Semin Immunopathol (2009) 31:283–307.
- Harrison’s Principles of Internal Medicine 17th edition