Barrett’s esophagus is a condition where the inner lining of the esophagus changes to resemble the intestinal lining. It predisposes the patient to cancer.
The esophagus is a 25 cms tube that connects the throat to the stomach and is the food pipe that lies behind the wind pipe. It consists of muscles lined on the inside by particular type of cells.
Norman Barrett, a British surgeon first described this condition, hence it is named after him. Following Barrett’s esophagus, some cells could show precancerous changes. This stage is called low-grade dysplasia. It could further progress to high-grade dysplasia and cancer.
The exact extent of the disease in the general population is not known since very few studies have been conducted on this topic. From the available information, it is estimated that the disease is less common in Asians than in the Western population.
The rate of patients with Barrett’s esophagus developing cancer is less than 1% per year. Despite this, it is necessary to detect it since esophageal cancer is very difficult to treat once it develops.
- Harrison’s Principles of Internal Medicine 17th edition
- Wood RK and Yang Y. Barrett’s Esophagus in 2008: an Update. Keio J Med 2008; 57 (3): 132-138
- Shalauta MD, Saad R. Barrett’s Esophagus. American Family Physician 2004, 69 (9): 2113-2118
Latest Publications and Research on Barrett’s EsophagusRisk of Cancer in Patients With Barrett Esophagus. - Published by PubMed
Identification of loci of functional relevance to Barrett's esophagus and esophageal adenocarcinoma: Cross-referencing of expression quantitative trait loci data from disease-relevant tissues with genetic association data. - Published by PubMed
Association between skeletal muscle attenuation and gastroesophageal reflux disease: A health check-up cohort study. - Published by PubMed
Diagnosing dysplasia in Barrett's oesophagus still requires Seattle protocol biopsy in the era of modern video endoscopy: results from a tertiary centre Barrett's dysplasia database. - Published by PubMed
To err is human: it is time to look forward in the management of Barrett's esophagus. - Published by PubMed