Current Research on Amyotrophic Lateral Sclerosis (ALS)

The National Institute of Neurological Disorders and Stroke, which is associated with National Institutes of Health (NIH), USA, provides plenty of support to biomedical research on ALS.

The main goals of the research on ALS are to:

Identify the cause (s) of ALS
Understand the mechanisms involved in disease progression
Develop treatment for ALS

The parameters involved in the study include the following:

Understanding how select motor neurons degenerate in ALS and finding ways to halt motor neuron damage
Study the role of SOD1 mutations in neuron damage in animal models
Study the role of free radicals accumulation in neurodegenerative diseases, including ALS
Understand the involvement of the loss of neurotrophic factors in ALS
Find out the role of apoptosis in ALS
Identifying a reliable and common biological marker for ALS that will allow early detection
Identify the involvement of other genes, besides SOD1 genes
Develop potential therapies for ALS through animal model studies

Published on Nov 12, 2009
Last Updated on May 07, 2018

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Dr. Reeja Tharu. 2021. Current Research on Amyotrophic Lateral Sclerosis (ALS). Medindia, viewed May 18, 2022, https://www.medindia.net/patients/patientinfo/amyotrophic-lateral-sclerosis-research.htm.

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mnarciastewart

With my amyotrophic lateral sclerosis [ALS], the first thing that happened almost 2 years ago now, was speaking as if I were drunk. I wasn't. I initially did improve speech (articulating clearly but slow) but now I can no longer speak in an acceptable way. Then, a year later eating became problematic, I was biting my tongue and lips, and chewing became weak and less controlled. Soon after that some fingers started to fail me and things would drop out of my hands. Somewhere at that time bulbar ALS was diagnosed. The Rilutek (riluzole) did very little to help me. The medical team did even less. My decline was rapid and devastating.. We tried every shot available but nothing was working. There has been little if any progress in finding a reliable treatment, Our care provider introduced us to Kycuyu Health Clinic ALS/MND herbal treatment. The treatment is a miracle.i recovered significantly! Visit www. kycuyuhealthclinic. com

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glen66t

My ALS [Amyotrophic lateral sclerosis] Symptoms started out with a "foot drop" on my left foot. From there my left leg lost all muscle tone and the entire left leg muscles are gone. Also my fingers and thumbs "contract" at times. Left arm loses muscle tone too. My family doctor said there is no cure for ALS, I was just living unhappy life till I saw a blog talking about Best Health Herbal Centre. So many people said positive things about their herbal product which I don’t believe at first. I showed my daughter what I saw online about their product and my daughter decided we shall give it a try. Few days later she purchased two bottle of ALS herbal remedy which they said I will use for only six weeks. My life changed automatically after six weeks of applying the herbal remedy as instructed. All my symptoms was terminated completely and am now living ALS FREE .. All Thanks to Best Health Herbal Centre for their good work in people’s life. For more details about their herbal product visit their Homepage w ww .besthealthherbalcentre. co m

Andrea59

Are there any new treatments for Als?

hopeforjoy

My dearest friend, Joy Styles, died from ALS on July 1st 2011. She was only 52. She was running half marathons and was very active when she noticed an atrophy in her left and and a weakness in her right leg. I have created a website in her name http://www.hopeforjoy.ca that is about her and has useful information about the disease. I wish I could do more, but every little bit helps. God bless everyone who has had experience with this terrible disease.

Doctor_Lilly

My symptoms started off with extreme muscle spasms and cramps. It would get worse when I was on my monthly. I was walking and running at the time to lose some weight that I thought was causing the muscle aches, headaches, and the pain that I was feeling in my whole body. One day it got overwhelming. It was August 17th, 2007. I felt like I was getting the life squeezed out of me and my mind was racing the whole time while experiencing difficulty speaking, walking, and trying to control the jerky movements. I was admitted as a psychiatric patient at that time, now it's been two years later and I feel like I am disseminating. I had another attack recently and that is what scared me enough to go to the neurologist. I am still afraid. I want to see it, and I'm interested in the damage that my body has endured. Can't wait to start treatment. Findyourdrug.com

Current Research on Amyotrophic Lateral Sclerosis (ALS)