Last Updated on Jun 22, 2020

AML - Future Hope

  • Intensive research on leukemia is being done at many cancer research centers to unravel the mystery behind the changes in an individual’s DNA that induces normal bone marrow cells to become abnormal. A treatment may result, once the information unfolds, with the abnormal DNA being substituted with the normal DNA, to restore cell growth.
  • Great strides have been taken to detect leukemic cells after treatment. Polymerase Chain Reaction (PCR) can detect a single cancer cell among a million normal cells. This is useful in checking out the effectiveness of the treatment.
  • Studies are being carried out to analyze the best combination of chemotherapy drugs and also to figure out the group of patients who will benefit the most from the various treatments.
  • Drug-resistance of the leukemic cells is another area that is being researched
  • Drugs that specifically target genetic changes associated with AML are being developed.
  • The mini-transplant is a modified blood stem-cell transplant procedure that involves very little total body irradiation followed by a stem-cell infusion. This method results in very few acute side effects, is more tolerable for both younger and older patients, and does not involve hospitalization.
  • The Hutchinson Center has developed a sensitive test that can identify the earliest signs of relapse by detecting one in a million cancer cells, enabling the doctors to quickly initiate treatment in patients whose disease is recurring after the induction treatment.
  • It was found by the Hutchinson Center researchers that children with aggressive leukemia, whose cancer recurred after a stem cell transplant, could be cured by a second transplant from a tissue-matched donor
  • Monoclonal Antibodies are specific proteins made in the lab, designed to attach to certain molecules on the surface of AML cells. Some of these antibodies have radioactive chemicals attached to them. When they are injected into an AML patient, they attach to the cancerous cells and destroy them. The first FDA-approved, antibody-targeted drug, Mylotarg, has been developed for use in older adults with AML who have suffered a relapse after treatment or who might be unable to withstand the side effects of further chemotherapy. Continued research is going on to consider the best use of this approach.


PurushNaidu Friday, December 20, 2013

my friend surfing with acute myeloblastic leukemia with maturation. Now he going on chemotherapy. He is on my 2nd session[0, 1 ,2]. Still two more session as per the doctor. Also Doctor's told good progress. I want to know what type of food will add more value to get more immunity. Please give some suggestion on food from nature.

epikia Tuesday, November 27, 2012

Hi.. i am 23 years old diagnose with AML last October 2012 and currently receiving chemotherapy. i am on my 2nd session and my doctor said i will have another session this december. id like to know when they say 5 years survival does that mean i only have 5years left eventhough i take my chemotherapy?

Vikram_Muddya Thursday, November 29, 2012

No, that only means that they certify that your cancer is cured only after 5 years, till then they monitor and see that it doesn't relapse by then.

mehul23 Tuesday, June 12, 2012

78 years aged mother suffering from lukemia pls tell me about the effective medicine and tell me about the chancec or not for recovery.. and which medicine are good for the acute lukemia pls write some medicines name for the recovery for the patitent Tuesday, December 4, 2012

plz take your mother to cancer hospital.the medicine is depends up on the type of leukemia.

Ravikohli Tuesday, February 28, 2012

I have Acute Leukemia[AML] cancer to my sister. Her age is 25 years. In recent test reports Blast are about 80%. Can you please tell me how i can proceed to cure my sister.

Nimat Wednesday, February 2, 2011

Hello.i just read about AML and i am satisfied with the information providede. Though i have one small enquiry; Anthracycline has been listed as one of the drugs given during Chemotherapy that may cause AML in the future and yet it has been listed as a drug for treating AML. Doess it mean that you are at risk of contracting AML again? I will apprecite your assistance on this qustion..

simipaknikar Sunday, February 6, 2011

Anthracyclines have been found to produce AML in patients who underwent treatment for breast cancer and Hodgkin's lymphoma, especially when used with other anticancer drugs and in high doses. Currently anthracyclines are very effective in AML, and the risk of them causing AML are small, hence they are used in AML.

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