About Careers Internship MedBlogs Contact us

Actinic Keratosis

Written by Avinash Ramani, M.S. (Biotechnology)  | Medically Reviewed by dr. simi paknikar, MD on Jun 11, 2014
Font : A-A+


Actinic Keratosis or Solar Keratosis is a pre-cancerous condition characterized by thick, rough, dry and scaly or crusty patches caused due to long, perennial exposure to sun.


The patches or lesions are more commonly seen in fair-skinned and old people and people who are often exposed to sun for long period. Actinic keratosis is caused due to solar damage, hence also called as Solar Keratosis.

Actinic Keratosis / Solar Keratosis

The lesions or patches can be 2 mm to 3cm in size and can be tan, pink, red or brown or a mixture of all these colors. Keratosis patches are typically harmless, however are often itchy and look ugly. Untreated lesions are at a risk of turning malignant and developing into squamous cell carcinoma.

These patches may typically appear on the sun-exposed area, such as the face, ears, neck, scalp, back of hands, forearms, elbows, or even in the lips. The patches start like rough scaly patches of dry skin and progresses to become a tough, wart-like lesions. They can sometime become very thick and look like horns or spikes.


Immuno-compromised people such as diabetics, cancer patients, HIV patients and organ transplant recipients are up to 250 times more susceptible to develop solar keratosis than others.

Men are more affected than women.

Causes of Actinic Keratosis

Actinic Keratosis is caused due to over-exposure to sunlight. The common risk factors for developing Actinic Keratosis are:

Causes of Actinic Keratosis: Over-exposure to Sunlight
  • Age above 40 years.
  • Hot and sunny climate.
  • Fair or pale skin, blue or green eyes, and blond or red hair.
  • History of many, severe sunburns early in life.
  • Tendency to freckle or burn when exposed to sunlight.
  • Weak immune system due to diabetes, chronic leukemia, chemotherapy, AIDS or because of immuno-suppressant medications for kidney or other organ transplant.
  • Working Outdoors and spending a lot of time each day in the sun.

Symptoms of Actinic Keratosis

The Symptoms and Signs of Actinic Keratosis are:

  • Rough, dry or scaly patches on skin, usually less than 2 inches (3 centimeters) in diameter.
Symptoms of Actinic Keratosis: Rough, Dry or Scaly patches on Skin
  • Flat or slightly raised patch or bump on the skin.
  • A hard, wart-like surface over the patches or lesions.
  • Colors as varied as pink, tan, red or brown, or flesh-colored.
  • Itching or burning sensation in the affected area.
  • Actinic keratoses are found primarily on areas exposed to the sun, like face, lips, ears, back of hands, forearms, elbows, scalp and neck.

Diagnosis of Actinic Keratosis

Physicians can usually diagnose actinic keratosis from their appearance or by doing a thorough physical examination of the lesions or patches. A biopsy is recommended when the keratosis is large or thick, to rule out the possibility of malignancy.

Treatment of Actinic Keratosis

Doctors may recommend to carefully monitor the patches and also ask to immediately turn to hospital if the patches / lesions cause any trouble.

5-fluorouracil is the most effective treatment often recommended. Local imiquimod and diclofenac gel is also used. The cream or gel is to be applied daily for several weeks. Repeated application causes the abnormal skin cells to die, and set normal after a few days of treatment.

Treatment of Actinic Keratosis: Fluorouracil

Various other treatments may also be used including:

  • Cryosurgery, or cryotherapy with liquid nitrogen, by "freezing off" the actinic keratosis. Freezing causes blistering and shedding of the sun-damaged skin.
  • Photodynamic therapy: It involves injecting a chemical into the bloodstream, which makes the lesions more sensitive to any form of light. Laser, notably CO2 and Er:YAG lasers is used to diffuse actinic keratosis.
  • Electrocautery: burning off actinic keratosis with electricity.
  • Different forms of surgery to cut-out the lesions. Removing the patch leaves a permanent scar. A regular follow-up after the treatment is advised to ensure no new lesions have developed and that no old ones have become thicker.


  1. Actinic keratosis - (http://www.nlm.nih.gov/medlineplus/ency/article/000827.htm)
  2. About Actinic keratosis - (https://www.mayoclinic.org/diseases-conditions/actinic-keratosis/symptoms-causes/syc-20354969)
  3. Actinic keratosis - Wikipedia - (https://en.wikipedia.org/wiki/Actinic_keratosis)
  4. Actinic Keratosis - Overview - (https://www.skincancer.org/skin-cancer-information/actinic-keratosis/)

Latest Publications and Research on Actinic Keratosis

Citations   close

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Avinash Ramani. (2014, June 11). Actinic Keratosis | Solar Keratosis - Causes Symptoms Signs Diagnosis Treatment. Medindia. Retrieved on May 28, 2022 from https://www.medindia.net/patients/patientinfo/actinic-keratosis.htm.

  • MLA

    Avinash Ramani. "Actinic Keratosis | Solar Keratosis - Causes Symptoms Signs Diagnosis Treatment". Medindia. May 28, 2022. <https://www.medindia.net/patients/patientinfo/actinic-keratosis.htm>.

  • Chicago

    Avinash Ramani. "Actinic Keratosis | Solar Keratosis - Causes Symptoms Signs Diagnosis Treatment". Medindia. https://www.medindia.net/patients/patientinfo/actinic-keratosis.htm. (accessed May 28, 2022).

  • Harvard

    Avinash Ramani. 2021. Actinic Keratosis | Solar Keratosis - Causes Symptoms Signs Diagnosis Treatment. Medindia, viewed May 28, 2022, https://www.medindia.net/patients/patientinfo/actinic-keratosis.htm.

Do you wish to consult a Dermatologist for your problem? Ask your question

Dr. Asifa N
Dr. Asifa  N
5 years experience
Teleconsult Now View Profile
Dr. Rashmi Naldeega
Dr. Rashmi Naldeega
5 years experience
Teleconsult Now View Profile
Dr. Vijay Gupta
Dr. Vijay  Gupta
9 years experience
SKINCITY, pilibhitbypass Road
Teleconsult Now View Profile
View All

Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.



Aldara is a topical cream used to treat genital warts, minor form of superficial skin cancers and actinic keratoses.

Health Topics A - Z

    Drugs for Actinic Keratosis
    What's New on Medindia
    Monkeypox Outbreak: What it is, How Does it Spread & the Prevention
    Seasonal Allergy Medications
    How to Choose the Best Eczema-Friendly Moisturizer for Children?
    View all

    Medindia Newsletters Subscribe to our Free Newsletters!
    Terms & Conditions and Privacy Policy.

    Most Popular on Medindia

    Blood Pressure Calculator Iron Intake Calculator Pregnancy Confirmation Calculator Find a Hospital Color Blindness Calculator Drug Interaction Checker Nutam (400mg) (Piracetam) How to Reduce School Bag Weight - Simple Tips Hearing Loss Calculator Indian Medical Journals

    Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

    © All Rights Reserved 1997 - 2022

    This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use