About
Acromegaly is a Greek word meaning enlargement of the extremities. It is a hormonal disorder that results when the pituitary gland produces excessive growth hormone (GH) in adulthood after attainment of puberty.
The incidence of Acromegaly is about 3-4 cases per million population per year. The disease mostly affects middle-aged adults and the mean age of diagnosis is 40-45 years. It can result in serious illness and premature death.

Acromegaly is often related to gigantism.
There exists a disease specially characterized by an hypertrophy of the hands, feet, and face, which we propose to call Acromegaly; that is to say, hypertrophy of the hands and feet "not because the hands and feet are alone affected during the course of the malady, but because their increase is an initial lesion, and constitutes the most characteristic feature of the affection". - Pierre Marie,1885
Acromegaly - Reference:
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Dr. Sangamithra. (2014, September 05). Acromegaly - Causes Symptoms Complications Diagnosis Treatment Prognosis. Medindia. Retrieved on Mar 31, 2023 from https://www.medindia.net/patients/patientinfo/acromegaly.htm.
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Dr. Sangamithra. 2021. Acromegaly - Causes Symptoms Complications Diagnosis Treatment Prognosis. Medindia, viewed Mar 31, 2023, https://www.medindia.net/patients/patientinfo/acromegaly.htm.
Latest Publications and Research on Acromegaly
- Voice Characteristics in Patients with Acromegaly during Treatment. - Published by PubMed
- An early scientific report on acromegaly: solving an intriguing endocrinological (c)old case? - Published by PubMed
- Italian Association Of Clinical Endocrinologists (Ame) And Italian Aace Chapter Position Statement For Clinical Practice: Acromegaly - Part 2: Therapeutic Issues. - Published by PubMed
- The haemostatic system in acromegaly: a single-centre case-control study. - Published by PubMed
- ITALIAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS (AME) and ITALIAN AACE CHAPTER POSITION STATEMENT FOR CLINICAL PRACTICE: ACROMEGALY - PART 1: DIAGNOSTIC AND CLINICAL ISSUES. - Published by PubMed
Readers may also be interested to read my summary about the latest guidelines for acromegaly. http://doiop.com/AcromegalyGuidelines
I was diagnosed with a pituitary tumor in 2005. It was a late stage macroadenoma. I have had surgery, gamma knife radiation and I have had 2 years of sandostatin. I still never feel good. I have lots of fatigue, muscle weakness and I take a lot of medicine. Can anyone give me any good news on this. My email address is triplejent@hotmail.com. I would love to hear from some other acromegaly patients to hear their stories. Mine has been a nightmare. I was sick and not feeling well for quite sometime, fatigue like no other actually exhaustion to where I was nauseated and sometimes vomiting when I got home from work. Finally told my husband that I either had something wrong with my heart or I had cancer. I was having a lot of palpitations and chest pain so I was sent to a cardiologist my first go around and they didn't pick up on it was going to ablate the areas on my heart that were beating irraticaly. I just need to hear someone elses story. Please email me. Thank you. Kayla
hi Kayla, i too had a macroadenoma which was removed in 06 but did not need drugs however i too have profound fatigue and do not feel good at all. I now have bad joints everywhere and have had 3 total knee replacements and have also got Parkinson's disease. My quality of life is doing down the slippery slope. I am under so many specialists but none seem really interested. It is a lonely battle to get well and sometimes i wonder if i ever will but will not give up! good luck. Where do you live? snurff
You can read longer article here http://www.genericlook.com/diseases/Acromegaly/. Hope it will help you...
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