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Acromegaly - Glossary

Written by Dr. Sangamithra, MBBS | Medically Reviewed by The Medindia Medical Review Team  on Sep 05, 2014
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Acromegaly - Glossary

Adenoma - General term for a benign tumor of a gland.

Cardiovascular diseases - Diseases of the heart and/or blood vessels.
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Carpal tunnel syndrome - Condition caused by compression of median nerve at the wrist often from repetitive motion.

Computed tomography (CT) scan - An x-ray technique that produces cross-sectional images of tissue structures through the body.

Diabetes mellitus - A chronic syndrome of impaired glucose metabolism due to insufficient secretion or relative deficiency of insulin.

Endocrine system - A regulatory system comprised of the endocrine glands that controls vital body functions such as metabolic activity, growth, and reproduction.

GH receptor agonist (GHRA) - A type of drug that blocks GH action peripherally and decreases IGF-1 production.

Gigantism - A condition caused by excessive secretion of growth hormones in childhood.

Growth hormone (GH) - A substance secreted by the pituitary gland that stimulates growth of bones and soft tissue in children and regulates metabolism in adults.

Hormone - A substance that is secreted by one gland or tissue and transported in blood to act on a distant organ or tissue.

Hypothalamus - Part of the endocrine system that helps activate and control the pituitary.

Headache - Pain or discomfort of the head, upper face, scalp, or neck region.

Impotence - Inability to attain or sustain an erection.

Insulin-like growth factor 1 (IGF-1) - A growth factor made predominantly in the liver; its levels increase in response to increased levels of GH.

Menstrual condition - Any conditions related to menstruation irregularities.

Magnetic resonance imaging (MRI) - A method of obtaining three-dimensional views of body organs using radiofrequency waves and intense magnetic fields.

Oral glucose tolerance test (OGTT) - A test used to assess the body's ability to utilize glucose.
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Pituitary - A small gland located at the base of the brain behind the eyes. The pituitary secretes hormones that directly or indirectly affect most basic bodily functions.

Radiotherapy - The use of radiation to kill rapidly growing tumor cells.

Secretion - A substance produced by a tissue that may be retained in the body or released from the body.

Somatostatin - The naturally occurring hormone produced in many parts of the body that signals the pituitary to reduce the production of GH.

Swollen bone - Enlarged, swollen, or misshapen bones.

Tumor - A pathological tissue growth, characterized by uncontrolled multiplication of cells.

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Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.

Comments

JonDanzig

Readers may also be interested to read my summary about the latest guidelines for acromegaly. http://doiop.com/AcromegalyGuidelines

Kayla-S-M

I was diagnosed with a pituitary tumor in 2005. It was a late stage macroadenoma. I have had surgery, gamma knife radiation and I have had 2 years of sandostatin. I still never feel good. I have lots of fatigue, muscle weakness and I take a lot of medicine. Can anyone give me any good news on this. My email address is triplejent@hotmail.com. I would love to hear from some other acromegaly patients to hear their stories. Mine has been a nightmare. I was sick and not feeling well for quite sometime, fatigue like no other actually exhaustion to where I was nauseated and sometimes vomiting when I got home from work. Finally told my husband that I either had something wrong with my heart or I had cancer. I was having a lot of palpitations and chest pain so I was sent to a cardiologist my first go around and they didn't pick up on it was going to ablate the areas on my heart that were beating irraticaly. I just need to hear someone elses story. Please email me. Thank you. Kayla

smurff

hi Kayla, i too had a macroadenoma which was removed in 06 but did not need drugs however i too have profound fatigue and do not feel good at all. I now have bad joints everywhere and have had 3 total knee replacements and have also got Parkinson's disease. My quality of life is doing down the slippery slope. I am under so many specialists but none seem really interested. It is a lonely battle to get well and sometimes i wonder if i ever will but will not give up! good luck. Where do you live? snurff

mar4ela

You can read longer article here http://www.genericlook.com/diseases/Acromegaly/. Hope it will help you...

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