Overview - Reflux Esophagitis
Esophagitis is a condition due to an inflammation of the lining of the lower end of the oesophagus. Esophagus or gullet is a hollow muscular tube about 2 cms in diameter that acts as the 'swallowing pipe' leading to the stomach. Muscles of the esophagus contract in a co-ordinated fashion in one direction to push the food down through a valve like muscle called the lower esophageal sphincter.
Reflux esophagitis is usually caused when the digestive juices containing acids from the stomach, repeatedly move upwards into the lower esophagus (reflux). Normally this is prevented by the one way check valve mentioned earlier called the lower esophageal sphincter.
This condition is also called -
- Gastroesophageal Reflux Disease (GERD)
- Heart Burn
- Acid regurgitation.
Esophagitis usually affects over-weight people more commonly especially when they reach the middle age of life. It is estimated that about 30% of adults experience occasional heartburn and about 10% experience heartburn almost daily. Heartburn is more common in pregnancy and about 25% suffer from it.
- Schwann, Theodor. Über das Wesen des Verdauungsprocesses. Arch Anat Physiol Wissensch Med. 1836; 90-138 [Reprinted in Selected Readings in the History of Physiology, 2nd ed. Translated by Fulton JF, Wilson LG. Springfield, IL: Charles C Thomas; 1966, pp. 190-2.
- Manipal Manual Of Surgery: K. Rajgopal Shenoy. MBBS, MS. (2000 EDITION)
Latest Publications and Research on Reflux Esophagitis
- Prevalence of non-obstructive dysphagia in patients with heartburn and regurgitation. - Published by PubMed
- In Barrett's Epithelial Cells, Weakly Acidic Bile Salt Solutions Cause Oxidative DNA Damage with Response and Repair Mediated by p38. - Published by PubMed
- Clinical utility of salivary pepsin measurement in patients with proton pump inhibitor-refractory gastroesophageal reflux disease symptoms: a prospective comparative study. - Published by PubMed
- Factors that predict a poor response to radiofrequency ablation for Barrett's oesophagus with dysplasia. - Published by PubMed
- Size-dependent differences in the proximal remnant stomach: how much does a small remnant stomach after subtotal gastrectomy work? - Published by PubMed