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Prune Belly Syndrome - Symptoms Treatment Complications Prognosis

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Alternative names - Eagle Barrett Syndrome, Triad Syndrome

Prune belly syndrome is characterized by an absence of abdominal muscles, severe abnormalities of the urinary tract and undescended testes.

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Prune belly syndrome is a rare condition that affects approximately one child among 30,000 to 40,000 live births. It usually affects only male children.

Prune Belly Syndrome

It is present from birth and is characterized by the following three features:

  • Absence of abdominal muscles
  • Severe structural abnormalities of the urinary tract
  • Cryptorchidism or undescended testes

The condition is called prune belly syndrome due to the wrinkled appearance of the abdomen, which results in resemblance of the child to a dried plum. It is also referred to as the triad syndrome, Eagle-Barrett syndrome, or the abdominal muscle deficiency syndrome.

Prune belly syndrome occurs due to a developmental abnormality when the fetus is within the uterus. A number of theories have been proposed to explain why it occurs, though the exact reason is not yet clear. While in the uterus, the fetus may suffer from pulmonary hypoplasia, a condition where the development of lungs is affected, and oligohydramnios, where the amount of fluid surrounding the fetus may be reduced. Many babies affected with this condition are stillborn.

Some variations in the condition have been noted. For example, in pseudo prune belly syndrome, urinary tract abnormalities are observed but the abdominal muscles are intact and the testes may be normally positioned in the scrotum. Patients with prune belly-like variant show abdominal wall defects; however, they do not show urinary tract problems.

Other problems related to the heart, digestive tract, bones and muscles may also be observed in some affected children.

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Children with prune belly syndrome are frequently prone to urinary tract infections. Antibiotics are used to prevent as well as treat these infections. Surgical correction is required in cases of urinary tract obstruction, for reconstruction of the abdominal wall, and treatment of undescended testes. Children with kidney failure may benefit from kidney transplantation.

Prognosis or outcome of the disease is poor in children with reduced lung or kidney function. Death could occur from lung complications or kidney failure.

Latest Publications and Research on Prune Belly Syndrome

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Dr. Nandita Gautam
Dr. Nandita Gautam
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Dr. Karthika  Karthikeyan
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Comments

cwxyz1

hmm...well my name is chris whit[not full last name]...I'm born with prune belly syndrome and to tell you all the truth...its not that bad...I just can't go out and do physical sports that would cause complications to my stomach...I've had surgeries when I was a kid due to falling down on a tree branch...I know it sucks...but again its not that bad...I don't really care for a cure because well its too late...have a good day yall

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