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Immunosuppression and Risk of Non Hodgkins Lymphoma (NHL)


Immunosuppression and Risk of Non Hodgkins Lymphoma (NHL)

Individuals who are immuno-suppressed e.g. those with AIDS have more risk to develop.

Non Hodgkin's Lymphoma (NHL) than others. They are-

  •  Those who have undergone an organ transplant, especially those who are in the first year after a transplant.
  •  Those with certain types of inherited immune deficiency syndromes. The following list of familial immune deficiencies with a predisposition for Lymphomas has been adapted from Chapters 19, 21, 45, and 47 of Magrath's text, The Non-Hodgkin's Lymphomas (1997):
  •  X-linked severe combined immunodeficiency (SCID).
  •  Omenn's syndrome.
  •  Purine nucleoside phosphorylase deficiency.
  •  Familial immunodeficiency appears to predispose certain families to more than the expected incidence of NHL
  •  X-linked agammaglobulinemia.
  •  Ig-A deficiency.
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  •  Common variable immune deficiency.
  •  X-linked hyper-IgM syndrome.
  •  IgG subclass deficiency.
  •  Wiskott-Aldrich syndrome.
  •  Ataxia telangiectasia.
  •  DiGeorge syndrome
  •  Hyper-IgE syndrome.
  •  X-linked lymphoproliferative syndrome.
  •  Chediak-Higashi syndrome.
  •  Bloom's syndrome.
  •  Enteropathy-associated T-cell lymphoma among northern Europeans.

Hashimoto's thyroiditis (for MALT lymphomas).

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