Neonatal Jaundice - Overview and History

The presence of excessive serum bilirubin in infants with Neonatal Jaundice imparts a yellow color to the skin.

The word 'Jaundice' is derived from the French word 'Jaune' meaning yellow. It is indicative of the yellow coloring of the skin of newborns with neonatal Jaundice, caused by the presence of excessive serum bilirubin.

Bilirubin, a yellowish-red pigment formed during the breakdown of red blood cells (RBC), is normally present in the blood in small quantities. When there is excessive red blood cell breakdown, the bilirubin level in the blood goes up and it also gets deposited in the tissues, imparting a yellow color to the skin.

There is a Disease, which has been called, Morbus Regius, or, The Royal Disease; because it brings with it the Colour of Gold unto them that have it. But so poor a Recommendation will not make the Jaundice to be wished for. The Excretion of the Bile into the Intestines, meets with some Obstruction, and so it Regurgitates and is Carried with the Blood all over the Body, whereby all the Parts, both the Solid and the Fluid, come to be tinged with a Yellow. - Cotton Mather, 1724.


  1. Mather, Cotton. The Angel of Bethesda. 1724 [Reprinted in Jones GW (ed). Barre, MA: American Antiquarian Society and Barre Publishers; 1972, p. 191.

Latest Publications and Research on Neonatal Jaundice


vaishali9524 Saturday, August 9, 2014

To prevent newborns from jaundice..keep your baby well hydrated with breast milk..and Frequent feedings [up to 12 times a day] encourage frequent bowel movements, which help remove bilirubin through the stools....

mehak464 Saturday, February 23, 2013

sir my baby billuribin ranges from 20-30 os this range is dangerous we also using phototherophy what u suggest.

avdhut85 Thursday, October 7, 2010

sir my baby's billrubin is 17 for how many days phototherapy shud be don

r.arunkumar Thursday, July 15, 2010

neonatal jaundice measurement by new technology using radiation

guest Tuesday, September 16, 2008

prevalence of kernicterus among Libyan full term healthy babies Discussion The results demonstrated that hyperbilirubinemia in full term otherwise healthy infants can lead to severe encephalopathy ,and what remain controversial is the bilirubin level that results in such injury, it is still undetermined whether a continuous linear relationship or a threshold level exists for bilirubin toxicity,we have noticed that all babies with serum bilirubin >40 mg developed Kernicterus ,and those with serum bilirubin ranges between 20-25mg had no kernicterus,and those with serum bilirubin ranges 25-35mg some developed Kernicterus and others had no adverse effect till now, although intellectual out come need years of follow up to declared that they are normal. we have seen that 34 babies out of 70 who received ET developed Kernicterus either because they seek medical advice late or their serum bilirubin was too high ,the other 8 babies who was not treated with ET, 5 of them developed Kernicterus on follow up . The prevalence of kernicterus among our babies was 15%,we tried to compare with worldwide prevalence.

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