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Muscular Dystrophy / Duchenne Muscular Dystrophy - DMD Treatment And Research

Written by Dr. Varshini Jayaraman,  Ph.D. | Medically Reviewed by Dr. Ramya Ananthakrishnan, MD on Apr 30, 2016
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DMD Treatment And Research

Treatment of DMD

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  • Despite the description of the disease as early as 1868, there is no reliable treatment for the muscle disease.
  • It is however possible to slow down the disease progress and preserve the muscle strength and joint function, enabling the patient to walk and sit.
  • As DMD affects nearly all the muscles of the body, a number of challenges have to be faced by those involved in the treatment process. A multi-disciplinary approach is needed for effective management of the disabling disease.
  • Various forms of treatment involving light weight braces and splints, physiotherapy, pulmonary therapy (breathing support) and surgery can be instituted.
  • The choice of a particular treatment largely depends on the clinical condition of the patient and the doctor's discretion.
  • Following identification of the DMD gene, researchers have developed animal models that mimic the disease. Such clinical experiments have now enhanced our pre-existing knowledge regarding the disease.
  • Active research is also being conducted to examine if injection of normal muscle cells (from healthy patients) or introduction of corrected form of the dystrophin gene into muscle cells (gene therapy) would reverse the disease process.
  • With such hope-giving treatment modalities on the horizon, a treatment for DMD is not so far.

References:

  1. Basic Human Genetics - Elaine Johansen Mange & Arthur P. Mange
  2. Medical Genetics - Lynn B. Jorde, John C. Carey, Raymond L. White
  3. Muscular Dystrophy - (http://www.nlm.nih.gov/medlineplus/musculardystrophy.html)
  4. Muscular Dystrophy Information Page - (http://www.ninds.nih.gov/disorders/md/md.htm)

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Comments

venkatakula

Hello All, My son is also suffering with DMD.he is 4 years old,i am from hyderabad, Does anyone get a proper guidance to fight against this diseases. If someone seriously got something please share with everybody. It will be a very good help to all those parents and patients who suffers lot

machu73

i would like mto be recieving videos on surgery,i am studying to be to be a surgeon.

anujverma

HELLO SIR MY NAME ANUJ .I AM 21 YEAR ONLY.. ME ALSO SUFFER IS PROBLEM 13 YEAR AND ME ALSO TAKE VITIMIONS AND EXCRSCIZE REGULERLLY BUT NO IMTRVEMENT PLZ HELP ME.. AND GIVE ME REPLY ..MY CONTACT NUMBER .8090875430

anujverma

helloo sir plz hel

Shiv.kumar

I have a hope for MD. May slow down the progression of MD and even stop the progression after 10-12 months. contact- 09416185485. many patients treated locally and posting this after 1 year of slowing down the 80% progression in them. Wishing a long and healthy life HAPPY FACES PRODUCE SMILES

anujverma

hello shiv mai anuj hu mujhko bhi yai problam hai plz kya tum thodi help kr skte ho plz dear plz call me 8090875430 plz ..

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