Written by Dr. Sangamithra, MBBS | 

Medically Reviewed by Dr. Ramya Ananthakrishnan, MD on Aug 07, 2020

Leprosy - Treatment

Dapsone is the first effective drug against leprosy but the bacteria developed resistance against the drug. Hence in 1970s the scenario shifted from monotherapy to Multiple Drug Therapy (MDT). The drugs used in WHO-MDT are a combination of rifampicin (600mg once a month), clofazimine (300 mg once a month and 50mg daily) and dapsone (100mg daily) for one year for Multibacillary (MB) leprosy patients and rifampicin (600mg once a month),and dapsone (100mg daily) for six months for Paucibacillary leprosy patients. For single skin Paucibacillary lesion single dose of

Rifampicin: 600 mg, Ofloxacin: 400 mg,and Minocycline: 100 mg is given. A minimum follow-up of 5 years is needed after completion of therapy in Multibacillary leprosy and a follow-up of 2 years in case of Puacibacillary cases.MDT is available free of cost from WHO.

Leprosy - References

  1. Leprosy elimination - (http://www.who.int/lep/)
  2. Leprosy - (http://www.nlm.nih.gov/medlineplus/ency/article/001347.htm)


sureshbbau768 Tuesday, August 6, 2013

hi this is sureshbabu.i have effected with hanseen disease,and i used MDT for one and half year,and doctors told to stop me and do some exercise..now main problem is one of my right hand fingers are clawed and it is shivering,and my skin turn into black on my face....tell me it is dangerous disease..how could i solve it i am doing small exercises but my fingers are same..please tell me and please helping to me...and my thinking too much on this unable to concentrate on anyhing...can i go to physiotheraphy...will the fingers come into normal...or can i go GYM and do exercises please please please help me....

shahnikunj Friday, March 15, 2013

its avery informative article thank you

gayani Wednesday, June 9, 2010

Is it dangerous in any way to make a patient who is undergoing treatment take up writing exercises as physiotherapy to get the fingers working again?The fingers are clawed in the right hand and the patient has been asked o come in for physiotherapy sessions as well

innocent14 Wednesday, March 17, 2010

Thanks a lot for providing qualitative & updated news about leprosy.Really this website has enhanced my leprosy knowledge.

dearmehraj Monday, September 7, 2009

i am a medical student requires a detail study of leprosy for seminar & i found your website very informative. Thank you, best regards.

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