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New classes of drugs like calcium sensitizing agents, vasopeptidase inhibitors, and natriuretic peptides are being studied in clinical trials.
Significant advancements have been made in the past 20 years. Exciting developments are still being researched for. New classes of drugs like calcium sensitizing agents, vasopeptidase inhibitors, and natriuretic peptides are being studied in clinical trials. The genetic association with heart failure is being studied, if positive results come in then we will see the advent of gene therapy in heart failure patients.
Appropriate lifestyle measures and medical regimens helps people with congestive heart failure to lead normal lives.
References:
- Cecil Medicine, 23rd Ed.
- Harrison''s PRINCIPLES OF INTERNAL MEDICINE, 17TH Edition
- Amsterdam EA. Revised American College of Cardiology/American Heart Association guidelines for the management of heart failure. Prev Cardiol. 2005 Fall;8(4):254, 256.
- Heart Failure Society Of America. Evaluation and management of patients with acute decompensated heart failure. J Card Fail. 2006 Feb;12(1):e86-e103. Review.
Congestive heart failure can affect many organs. For example: The weakened heart muscle may not be able to deliver enough blood to the kidneys, which in turn begin to lose their normal ability to excrete salt and water. This can cause decreased kidney function in the body to retain more fluid. The lungs can become clogged with fluid and the ability of the person to take down. The fluid can also accumulate in the liver, which hinders their ability to rid the body of toxins and produce essential proteins. The intestines can become less efficient in absorbing nutrients and drugs. The fluid can also accumulate in the extremities, causing swelling of the ankles and feet. http://www.insideheart.com