About Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Treatment for Chronic Lymphocytic Leukemia

Last Updated on Jun 22, 2016
Font : A-A+

Treatment for Chronic Lymphocytic Leukemia

Early stage CLL may take years to evolve. Doctors may recommend watchful waiting for some patients, depending on the disease stage.

Advertisement

Chronic Lymphocytic Leukemia (CLL) may remain stable for several years, but may evolve to become more aggressive, sometimes transforming into non-Hodgkin's lymphoma (Richter's transformation). If such changes occur, more aggressive treatment may be necessary.

The best approach for some patients may be to closely monitor their blood count regularly and to check for possible manifestation of a symptom, rather than undergoing any treatment.

Radiation Therapy is rarely used in the treatment of CLL.

The following are the basic tenets involved in CLL treatment-

  • Treatment of the newly diagnosed
  • Treatment of those with a progressive disease
  • Treatment of those whose disease is resistant to standard treatments
  • Treatment of complications / side-effects

Some of the popular treatment modes for CLL are -

  • Chemotherapy

Initial CLL treatments depends on

  • the exact diagnosis
  • the progression of the disease
  • the preference / experience of the health-care practitioner

There are dozens of drugs used for CLL therapy, and considerable research activity is taking place analysing them individually and also in combination with each other.

This treatment aims to destroy the abnormal cells present in the blood and the bone marrow, in order to facilitate the normal cells to multiply. Chemotherapy drugs are administered orally or intravenously. Patients undergoing chemotherapy are prone to infections because their immune system is impaired. To counter this, antibiotics are administered intravenously.

Corticosteroids, purine analogs, anti-tumor antibiotics, monoclonal antibodies, growth factors and cytokines are employed in the treatment of CLL.

Advertisement
  • Monoclonal antibody therapy

Monoclonal antibodies are artificial proteins that attack specific proteins on the malignant blood cells, causing them to die. Besides this function they also alert the body's immune system to eliminate other leukemic cells.

  • Surgery

Surgery may be required, sometimes, to biopsy the lymph node tissue or to remove the spleen, if it is enlarged.

  • Bone Marrow Transplant

Patients who do not respond to or benefit from other treatment options are ideal candidates for bone marrow transplants.

The first step towards a transplant is by treating the leukemia with chemo- and/or radio- therapy to suppress the immune system. Then healthy marrow cells, from a matching donor, are injected into the patient intravenously. These normal cells multiply and re-populate within the patient's bone marrow. The patient also benefits from the immune system components, found in the donor's marrow cells, which attack the leukemic cells by treating them like infection.

Chronic Lymphocytic Leukemia - Reference:

Citations   close

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Dr. Reeja Tharu. (2016, June 22). Treatment for Chronic Lymphocytic Leukemia. Medindia. Retrieved on May 23, 2022 from https://www.medindia.net/patients/patientinfo/chronic-lymphocytic-leukemia-treatment.htm.

  • MLA

    Dr. Reeja Tharu. "Treatment for Chronic Lymphocytic Leukemia". Medindia. May 23, 2022. <https://www.medindia.net/patients/patientinfo/chronic-lymphocytic-leukemia-treatment.htm>.

  • Chicago

    Dr. Reeja Tharu. "Treatment for Chronic Lymphocytic Leukemia". Medindia. https://www.medindia.net/patients/patientinfo/chronic-lymphocytic-leukemia-treatment.htm. (accessed May 23, 2022).

  • Harvard

    Dr. Reeja Tharu. 2021. Treatment for Chronic Lymphocytic Leukemia. Medindia, viewed May 23, 2022, https://www.medindia.net/patients/patientinfo/chronic-lymphocytic-leukemia-treatment.htm.


Post a Comment

Comments should be on the topic and should not be abusive. The editorial team reserves the right to review and moderate the comments posted on the site.

Comments

JLD1948

Can hyperbaric oxygen therapy be used to treat CLL ?? My Dad is 92 and mild diabetic. He was holding his own until a lymph gland swelled up under his arm; they did radiation; the tumor burst and is now an open wound under his arm. They are doing wound care; three times per week; but it is extremely painful for him. I know that the Hyperbaric treatments are beneficial for numerous wounds and ailments. Could it possibly be beneficial to heal this open would under his arm ?

jen71

My dad has been just diagnosed with cll. He is 65 yrs old, a smoker for about 50yrs. now. He said he has not felt right for about 4-5yrs. said he knew something was wrong. His white blood cell count is 280,000 and still fighting shingles. What is his prognosis?

dazedandconfused

I'm 48 years old and have had 7 heart attacks in the last 14 years along with 12 stents. Recently I was diagnosed with stage 4 CLL. Can you give me any ideas on life expectancy?

saba_mother

my mother is diagnosed with CLL, 63 is the count of platelets and 112400 of wbc what are te chances

wanda

Is CLL hereditary?

John66

Yes, my doctor told me it was. I have CLL and my brother and sister has it.

Advertisement
Health Topics A - Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z



    What's New on Medindia
    Can Weight Loss be Achieved by Drinking Water?
    Can Exercise Counts Boost Your Life Counts? 
    Prevent Hacking of Medical Devices: FDA Sounds Alarm
    View all

    Medindia Newsletters Subscribe to our Free Newsletters!
    Terms & Conditions and Privacy Policy.

    Most Popular on Medindia

    Blood Donation - Recipients Nutam (400mg) (Piracetam) Turmeric Powder - Health Benefits, Uses & Side Effects Sanatogen Drug Interaction Checker Find a Hospital Iron Intake Calculator Vent Forte (Theophylline) Selfie Addiction Calculator Blood Pressure Calculator

    Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

    © All Rights Reserved 1997 - 2022

    This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
    open close
    ASK A DOCTOR ONLINE