Last Updated on Jul 04, 2018

‘Cardiac marker genes are thought to participate in cardiomyocyte differentiation and to contribute to heart hypertrophy in animal models’, says the results published in Cardiovasc Pathol.2007 Nov-Dec;16(6):329-35. Epub 2007 Jun 20.

Early cardiac marker genes include: cardiac-specific homeobox (Csx/Nkx2.5), myocardin, homeodomain only protein, GATA4, and myocyte enhancer factor 2C. Altered expressions of early cardiac marker genes and differentiation-specific marker genes have been found in patients with the condition called hypertrophic cardiomyopathy.


  1. Cecil Medicine, 23rd Ed. Harrison's PRINCIPLES OF INTERNAL MEDICINE, 17TH Edition
  2. Cardiovasc Pathol. 2007 Nov-Dec;16(6):329-35. Epub 2007 Jun 20.
  3. INTERNATIONAL JOURNAL OF CLINICAL & LABORATORY RESEARCH Volume 29, Number 2, 56-63, DOI: 10.1007/s005990050064


Randox Monday, November 15, 2010

The ischemic biomarker Heart-type Fatty Acid Binding Protein [H-FABP] can substantially improve the detection of high risk patients when Troponin-negative, even when a high sensitivity assay is used, a new publication has shown. In the June edition of JACC, Professor Alistair Hall and colleagues from the University of Leeds, UK, prospectively studied a cohort of 1080 consecutive patients admitted to hospital with suspected ACS and compared the H-FABP assay (Randox Laboratories) with the high sensitivity Ultra-TnI assay (Siemens Healthcare Diagnostics).

Most Popular on Medindia