Last Updated on Feb 01, 2016

Sir 2 genes

Sirtuin, or Sir 2, genes play a role similar to calorie restriction and enhances longevity.

More than a decade ago, scientists at the MIT in the United States, began to delve into this amazing phenomenon. By employing molecular techniques, Drs.Leonard Guarente and David Sinclair discovered that the addition of a copy of the Sirtuin gene, Sir2, to yeast cells enhanced their longevity by 30 %. Further studies have revealed that these genes play a role in harnessing the goodness of calorie restriction.

An obvious question that crops up is - Do we have to deprive ourselves of food in order to kick-start these genes? The answer is No. Studies indicate that the Sir2 genes require a metabolite to activate it. By evaluating the metabolic activity, the gene initiates anti-ageing processes similar to those triggered by a restricted diet.

Comments

johnherron Wednesday, January 9, 2019

From decreased death rate to killing cancer cell, a small amount of wine at the end can go a long way when it comes to beneficial effect. Kills the antioxidants When choosing your wine for antioxidants, go with white wine preferably Boost the immune system Moderate alcohol can zone off infections and improve immune system in check. Improves bone Density Red wine has found to be highest levels of silicon, which best for your bone mineral density.

SankaranIyer Wednesday, November 25, 2009

Dear Sir, For the ageing problem to be slow we require the basic natural necessities i.e., clean air, clean water and clean environment. None of the above is present now anywhere in the world except perhaps in Amazon forest and congo forest. There also human beings have gone and slowly spoiling it. So called scientists take quantity x from nature and give back only x-1,2... In Hindu philosophy it is called Yuga characteristics. Nothing can be done except crying from rooftops to stop pollution. IT IS A PITY. HS NARAYANAN

guest Tuesday, September 30, 2008

Dear Sir, Article is excellent. I will be very thankful. Food restriction is the process which most probably will limit the load of OXYRADICALS in the system thereby postponing the Age Related changes. Please send me the references so that the issue of FOOD RESTRICTION and how it works can be cleared. Thanks Dr. VENUGOPAL

guest Monday, February 19, 2007

I sometimes wonder what is the so called "good" or "bad" in terms of diet.The dietary recommendations keep changing on a day to day basis. I suppose the good old practice of our ancestors to eat timely meals prepared from chemical free ingredients should do the trick.

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