Last Updated on Feb 01, 2016

Resveratrol Research

The Resveratrol-fed mice did not develop undesirable health conditions despite their high calorie diet.

In an effort to understand this better a pioneering study was carried out in the mammalian system using the mouse model. Research led by David Sinclair and Jos Baur of the Harvard medical school and Raphael de Cabo, of the National Institute of Ageing, studied the effect of Resveratrol on the motor skills of mice. They analyzed the efficacy with which the mice could balance and walk along a rotating rod before they fell off. Resveratrol- fed mice did a much better job as they grew older and demonstrated excellent endurance.

The subjects of the study were middle-aged rodents that were segregated into 3 groups fed on three different diets –

  1. A-Standard
  2. B-High- calorie, high-fat diet
  3. C-High-calorie, high-fat diet with Resveratrol

As expected, the group B mice developed undesirable conditions like obesity, inflammation of the heart muscles and a diabetes-like condition. These mice also met with an untimely death. However the group C mice, that were fed with Resveratrol demonstrated the following:

  • They did not develop any undesirable health conditions despite their high-calorie diet
  • They had the physiology of a normal lean mouse and demonstrated ample activity
  • They fared far better in physical tests and aerobic activities in comparison to the group B mice.
  • The group C mice were also able to run twice as far without feeling fatigued
  • These mice developed the capacity to consume oxygen more efficiently and were able to generate greater energy
  • The risk of death in the group C mice was reduced by 30%.

Actually, the group C mice were not prevented from growing big and the high-calorie diet did show on their tubby exteriors. Although they reveled in gluttony, these mice simply did not pay the price for their indulgence, as there was no demonstrable increase in the levels of glucose or insulin. Their life span too received a boost.

This study has been reported in the 2006 November issue of the journal ‘Nature’.


johnherron Wednesday, January 9, 2019

From decreased death rate to killing cancer cell, a small amount of wine at the end can go a long way when it comes to beneficial effect. Kills the antioxidants When choosing your wine for antioxidants, go with white wine preferably Boost the immune system Moderate alcohol can zone off infections and improve immune system in check. Improves bone Density Red wine has found to be highest levels of silicon, which best for your bone mineral density.

SankaranIyer Wednesday, November 25, 2009

Dear Sir, For the ageing problem to be slow we require the basic natural necessities i.e., clean air, clean water and clean environment. None of the above is present now anywhere in the world except perhaps in Amazon forest and congo forest. There also human beings have gone and slowly spoiling it. So called scientists take quantity x from nature and give back only x-1,2... In Hindu philosophy it is called Yuga characteristics. Nothing can be done except crying from rooftops to stop pollution. IT IS A PITY. HS NARAYANAN

guest Tuesday, September 30, 2008

Dear Sir, Article is excellent. I will be very thankful. Food restriction is the process which most probably will limit the load of OXYRADICALS in the system thereby postponing the Age Related changes. Please send me the references so that the issue of FOOD RESTRICTION and how it works can be cleared. Thanks Dr. VENUGOPAL

guest Monday, February 19, 2007

I sometimes wonder what is the so called "good" or "bad" in terms of diet.The dietary recommendations keep changing on a day to day basis. I suppose the good old practice of our ancestors to eat timely meals prepared from chemical free ingredients should do the trick.

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