| YEAR | MILESTONES |
| 1847 | Sir James Young Simpson a Scottish physician introduced chloroform as an anesthetic agent during childbirth. Chloroform was first used on Queen Victoria, during her eighth delivery. |
| 1847 | Edward H. Barton at Vera Cruz, Mexico was the first to use sulfuric ether as the anesthetic agent for a leg amputation during wartime. |
| 1856 | John Snow, an English physician designed the chloroform inhaler, which delivered the anesthetic agent at optimum levels. He was the first to perform endotracheal anesthesia on a rabbit. |
| 1860 | Etienne Jules Marey a French physician discovered the sphygmographe. This device helped to record the pulse form on the forearm. |
| 1870 | Joseph T Clover an English surgeon improved the techniques of gas delivery and cautioned the physicians to monitor the vital signs. |
| 1875 | Claude Bernard a French physiologist Discovered the nerve muscle blocking action and the introduced the use of mixed anesthesia. |
| 1878 | Paul Bert the French physiologist along with the American surgeon Edmund W Andrews introduced nitrous oxide in Anesthesiology. |
| 1907 | Frederick J. Cotton and Walter M. Boothby invented an apparatus for the delivery of nitrous oxide, ether and oxygen. |
| 1908 | A.D Waller designs the chloroform balance, which determines the concentration of the vapor, received by the patient. |
| 1910 | Lincoln F. Sise invented the apparatus “introducer” for insertion of lumbar puncture needles. |
| 1936 | American society of Anesthetist was founded. |
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great information, but kindly include some advance use of Anaesthesia in different OT stages. thanks
Im surprised, to know the ancient methods of anaesthesia like forceful knock on head, snow anaesthesia etc.