Acute Lymphoblastic Leukemia - Incidence

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Last Updated on Apr 04, 2018
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Incidence of Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia (ALL) can occur at all ages. However, it is most common in young children and older adults.

The incidence of Acute Lymphoblastic Leukemia (ALL) in Children below 15 years is approximately 3-4 cases per 100,000 children.

The following are some of the highlights of ALL incidence-

  • ALL is more prevalent in developed countries than in the developing ones. The magnitude of the disease appears to correlate with the socio-economic status.
  • There are approximately 2,400 children and adolescents below 20 years of age who are diagnosed with ALL each year in the United States.
  • A gradual increase in the incidence of ALL has been observed in the last 25 years.
  • ALL is the most common cancer among children with a peak incidence of 4-5 years of age. It accounts for 23% of childhood cancers (children younger than 15 years).
  • The incidence of ALL appears to be highest in Hispanic children; it is 3- fold higher for white children,aged 2-3 years, compared to black children of the same age
  • In adults, it is less common than Acute Myelogenous Leukemia (AML). In the United States, approximately 1000 new ALL cases occur in adults each year.
  • Only 20-40% of adults with ALL are cured with current treatment regimens
  • The highest incidence of ALL occurs in Italy, the United States, Switzerland, and Costa Rica
  • The annual rate of ALL occurrence is approximately 30 to 40 per million.

References:

  1. Pui CH. Acute lymphoblastic leukemia. Pediatr Clin North Am 1997; 4: 831-846.
  2. Pui CH, Evans WE. Acute lymphoblastic leukemia. N Engl J Med 1998; 339: 605-615.
  3. Gurney JG, Severson RK, Davis S, Robinson L. Incidence of cancer in children in the United States. Cancer 1995; 75: 2186-2195.
  4. Young J, Gloeckler RL, Silverberg E, Horm J, Miller R. Cancer incidence, survival and mortality for children younger than age 15 years. Cancer 1986; 58: 598-602.

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hi my daughter , rashmi 5 year old female was admitted in a hospital with the c/o fever,and anemia diagnosed as a ALL ,B CELL,started chemotherapy there at the time of admission her haemoglobin is 4,platelet 10,000,peripheral smear shows blast presnt CSF NEGATIVE BONE MARROW NOT DONE induction chemotherapy started prednisolone oral inj.vincristine i.v 4 doses inj, daunorubicin 3 doses inj.L. asparaginase 8 doses IT ,methotrexate 3 times BONE MARRO DONE 3? BLAST SHOWS phase b inj.cyclophosphamide iv 2 time inj,cytarabine s/c [ arac] 4 days * 4 doses tab .6 mp 60 days IT METHOTREXATE 3 times tab.biotraxate RE INDUCTION PHASE tab.dexamethasone orally inj.vincristine iv 4 doses inj. dnr 4 doses inj.L .asparanginase 4 dose inj.cyclophosphamide 1 dose inj.cytarabine 2 dose it.methotrexate 2 doses BONE MARROW DONE SHOWS 3% BLASTS AND 5%LYMPHS CSF NEGATIVE given tab.6pm for one month review 20/8/2012 please given valuable comments how is the condition and what to do next?

Toni95

Non of this has helped me with my research :/ my sister has leukemia and none of the stuff above is even close!!

jasperkumar

i had ALL WEN I WAS 10. I was treated for a year and i was good for 10 years but i was diagnosed for ALL wen I WAS 20 . I was treated and i am okay now. is this possible?

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