Health Benefits of CoQ10

Maulishree Jhawer
Article Reviewed by Dietitian  on Aug 27, 2014
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Health Benefits of CoQ10

Numerous investigators have established the normal blood levels of CoQ10. Significantly reduced amounts have been noted in cancer, heart disease and fatigue.

Heart Disease

Heart muscles, comprising perhaps the most important muscle in the body; contain the largest number of mitochondria. Investigators in the early 1980ís began trials in which patients took CoQ10 supplements. By the early 1980s cardiologists Peter Langsjoen, M.D., of Tyler, Texas, and his colleagues had started using CoQ10 to treat patients with cardiomyopathy and heart failure.

Early on Japanese doctors who treated patients with cardiomyopathy and heart failure (diseases caused not by cholesterol, but by a loss of energy in the heart) found that CoQ10 supplements helped bring back normal heart function in many of the patients.

In one of the largest international studies namely the Italian Multi-Centre Trial by Baggio and Associates, which involved 2,664 patients with heart failure, nearly 80 percent of the patients improved after taking the compound (50 to 150mg of standard CoQ10 (Ubiquinone) daily for three months) and 54 percent had major improvements in the symptoms. This was a landmark study and showed how nutritional medicine could work wonders.

CoQ10 should be used in support with the traditional medical treatment. According to experts, in case of heart failure, patients should be supplemented with CoQ10 over long term. If discontinued the needed fuel source becomes depleted again and heart function slowly decreases back to its previous level. According to research supplementation with 300 mg daily can significantly improve a weak heartís ability to pump blood.

Fatigue

CoQ10 can also boost energy levels and reduces fatigue.

According to Dr. Langsjoen 16 patients (80 to 88 years old) who took an average of 220 mg of CoQ10 daily for three months felt better and had less fatigue after physical exertion. The benefits lasted as long as the patients took the supplements and the patientsí heart function improved as well.

A study, conducted at Baylor University in Waco, Texas, found that both trained and untrained men and women had greater endurance after taking 200 mg of CoQ10 for two weeks.

Neurological Diseases

Brain cells require large amounts of energy, and CoQ10 can benefit some neurological disorders.

A study conducted at a few U.S. hospitals revealed that CoQ10 supplements reduced the symptoms and slowed the progression of Parkinsonís disease. The protocol included eighty patients being given 300, 600 or 1,200 mg of CoQ10 or placebos daily for sixteen weeks. All the patients taking CoQ10 had less severe symptoms than those in the placebo group. The highest dose provided the greatest benefits.

Breast Cancer and Other Cancers

In the 1990s, Danish surgeon Knud Lockwood, M.D., reported patient case histories in which post the supplementation of CoQ10 (almost 400 mg daily) there was inhibition of metastases (the spread of a disease to other parts of the body) in recurrent breast cancers. According to him CoQ10 did not have direct anti-tumor properties, but it probably helped energize the bodyís anti-cancer immune cells.

In 2009, Danish physician Niels Hertz, M.D., reported the results of 41 cancer patients who took 300 mg of CoQ10 and several other supplements in addition to the conventional therapies. Three-fourths of the patients lived an average of five months longer than expected and in many cases, patients lived two years longer than expected.

References:

  1. Coenzyme Q10 ó Energy for Life, Jack Challem, The Nutrition Reporterô
  2. Hertz N, Lister RE. Improved survival in patients with end-stage cancer treated with coenzyme Q10 and other antioxidants: a pilot study. Journal of International Medical Research, 2009;37:1961-1971
  3. Lockwood K, Moesgaard S, Yamamoto T, et al. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochemical and Biophysical Research Communications, 1995;212:172-177.
  4. Cooke M, Iosia M, Buford T, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr, 2008;5:8.
  5. Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. BioFactors, 2003;18:101-111.
  6. Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental coenzyme Q10 and statin drug discontinuation. BioFactors, 2005;25:147-152.
  7. Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. BioFactors, 2003;18:101-111.
  8. E Baggio, R. Gandini et al., ďItamian multi-centre study on the safety and efficacy of coenzyme Q10as adjunctive therapy in heart failure,Ē Molecular Aspects of Medicine, 15 (1994), 287-294
  9. Shults CW, Oakes D, Kieburtz K, et al. Effects of coenzyme Q10 in early Parkinson disease. Evidence of slowing of the functional decline. Archives of Neurology, 2002;59;1541-1550.
  10. Xtend Life Nutrition Supplements, Newzeland

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