CoQ10 Supplementation

Maulishree Jhawer
Article Reviewed by Dietitian  on Aug 27, 2014
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CoQ10 Supplementation

Muscles are the key to remaining youthful. Once there is a loss of muscle mass, the body packs on weight and a person feels old. To prevent this antioxidants like CoQ10 are required to fight the free radical damage that causes oxidative stress and physical degeneration.

Ubiquinol form of CoQ10 is the most important one for the heart and sustained energy.

The type of CoQ10 found in most supplements which has been around for years is called Ubiqui (none) - oxidized CoQ10. The body routinely converts ubiquinone to ubiquinol (reduced form and the active form). But, if one is over 40 years of age there is a need to take very large dose of ubiquinone to get the potential benefits as the ‘conversion’ is not very effective and as a result full benefits may not obtained.

Elderly people benefit from ubiquinol more, because it is better absorbed and requires no conversion.

When on prescription drugs, such as digitalis and ACE inhibitors for heart failure or cardiomyopathy, CoQ10 can prove to be a very beneficial additional supplement. One may even need less of the medicine post supplementation.

According to medical experts, below given is a general guideline for supplementation under normal conditions:

PRECAUTION: You need to consult a doctor regarding your intake of CoQ10 supplementation to avoid adverse affects.

  • 30 to 50 mg of CoQ10 daily for 20 to 30 years old
  • 100 mg daily for 30 to 50 years old
  • 200 mg daily for the age of 50 or above
  • 100 - 200 mg daily in case of heart ailments or dyslipidemia
  • 100 – 200 mg daily in case of chronic fatigue or fibromyalgia
  • 200 – 300 mg daily incase of multiple sclerosis
  • 300 – 600 mg daily in case of cardiomyopathy
  • 500 – 600 mg daily in case of metastatic cancer, half the dose for cancer stricken children

One can work it around with a nutritionally oriented physician or a nutritionist.

Energy-boosting effect can further be enhanced by taking L-carnitine (or acetyl-L-carnitine), alpha-lipoic acid, ribose, creatine monohydrate, and quercetin. For boosting the food intake of CoQ10, some organ meats, such as heart and liver could be included in the diet.

References:

  1. Coenzyme Q10 — Energy for Life, Jack Challem, The Nutrition Reporter™
  2. Hertz N, Lister RE. Improved survival in patients with end-stage cancer treated with coenzyme Q10 and other antioxidants: a pilot study. Journal of International Medical Research, 2009;37:1961-1971
  3. Lockwood K, Moesgaard S, Yamamoto T, et al. Progress on therapy of breast cancer with vitamin Q10 and the regression of metastases. Biochemical and Biophysical Research Communications, 1995;212:172-177.
  4. Cooke M, Iosia M, Buford T, et al. Effects of acute and 14-day coenzyme Q10 supplementation on exercise performance in both trained and untrained individuals. J Int Soc Sports Nutr, 2008;5:8.
  5. Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. BioFactors, 2003;18:101-111.
  6. Langsjoen PH, Langsjoen JO, Langsjoen AM, Lucas LA. Treatment of statin adverse effects with supplemental coenzyme Q10 and statin drug discontinuation. BioFactors, 2005;25:147-152.
  7. Langsjoen PH, Langsjoen AM. The clinical use of HMG CoA-reductase inhibitors and the associated depletion of coenzyme Q10. A review of animal and human publications. BioFactors, 2003;18:101-111.
  8. E Baggio, R. Gandini et al., “Itamian multi-centre study on the safety and efficacy of coenzyme Q10as adjunctive therapy in heart failure,” Molecular Aspects of Medicine, 15 (1994), 287-294
  9. Shults CW, Oakes D, Kieburtz K, et al. Effects of coenzyme Q10 in early Parkinson disease. Evidence of slowing of the functional decline. Archives of Neurology, 2002;59;1541-1550.
  10. Xtend Life Nutrition Supplements, Newzeland

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