Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

NRTIs are faulty versions of building blocks that HIV needs to make more copies of itself. When HIV uses an NRTI instead of a normal building block, reproduction of the virus is stalled.

Long term side effects of NRTIs have been associated with damage to the mitochondria (the cell parts that provide energy to the cell). This damage may cause low red and white blood cell counts, muscle pain and wasting (particularly in the arms and legs), fatigue, peripheral neuropathy, and more rarely, serious liver (lactic acidosis) or pancreas problems.

Nucleoside Reverse Transcriptase Inhibitors (NRTIs)

DrugDosageSide Effects
Retrovir / AZTOne 300 mg tablet daily.Nausea, stomach discomfort, headache, insomnia, muscle wasting, anemia, neutropenia (low white blood cell count). Medicine should be taken with food to reduce the stomach discomfort.
Epivir / 3TCOne 300 mg tablet daily.Nausea Epivir is also taken for treatment of Hepatitis B virus, but with a different dosage.
Combivir / AZT + 3TCOne tablet (300 mg AZT + 150 mg 3TC).Nausea, vomiting, headache, loss of appetite, fatigue, stomach discomfort, Muscle wasting, anemia (low blood cell count), neutropenia (low white blood cell count).
Trizivir / AZT + 3TC + AbacavirOne tablet (300 mg AZT + 150 mg 3TC + 300 mg Abacavir) twice daily.Nausea, stomach discomfort, headache, insomnia, muscle wasting, anemia, neutropenia (low white blood cell count).
Ziagen / AbacavirOne 300 mg tablet twice daily.Nausea, vomiting, diarrhea, loss of appetite, insomnia, serious allergic reactions in 3-5% of patients with one death. The signs include - fever, mailaise, nausea, diarrhea, abdominal pain, sore throat, cough, shortness of breath, and rash.
Videx / ddl
Numbness, lingling, or pain in the hands or feet, nausea, vomiting, diarrhea, headache and rash, Pancreatitis (inflammation of pancreas)
Zeritt / d4TOne 40 mg capsule, every 12 hours.Numbness, tingling, or pain in the hands or feet, nausea, diarrhea, vomiting, headache, rash, Pancreatitis, lactic acidosis.
HIVid / ddC0.75 mg tablet, every 8 hours.Numbness, tingling, or pain in the hands or feet, nausea, vomiting, mouth ulcers. Drug is to be taken in empty stomach.
Viread / tenofovirOne 300 mg tablet once a day.Nausea, vomiting, diarrhea, intestinal gas.
Emtriva / EmtricitabineOne 200 mg tablet daily.Headache, nausea, vomiting, diarrhea, rash.

Fusion Inhibitors prevent HIV entry into cells.

DrugDosageSide Effects
Fuzeon / T-20Two 90 mg subcutaneous injections per day.Skin reactions at the site of injection - itching, swelling, redness, pain or tenderness, hardened skin or bumps.


ethiopian_girl Thursday, September 6, 2012

am 19 years old i hv been wid hiv since i wz kid but i live wid out ant medicion till now but i start to get sick so fast am univresty student so wht do u suggest me?

perfectkhan Sunday, October 14, 2012

start medication. HIV virus didnt dominated you for long period. it was affecting your immune system now its effecting your health. Start the therapy as soon as possible

shweaung Sunday, May 6, 2012

how much cost for the treatment?

Kebede Wednesday, April 4, 2012

I am from Ethiopia aged 41. I didn't start the treatment and knew that I'm affected by the virus before 1 year am the man work serious place in gov't instituition. Now I want to start treatment immediately. I NEED SERIOUS help and advise from you. I do not want to die.

Drshaka Sunday, February 19, 2012

Hello,I am Tradomedical Doctor in Benin Rep the only one who heals and solves all failed problems. Stop suffering today! Change your life and archive your goals. No matter whom you are or religion you believe in, this type of treatment may be the only solutions to your problems with your long illness. Try this; you will see a better change! If you have tried many doctors/healers with no progress. if you think you have lost hope, here is an opportunity,our record speak for us, come over to biodynamic trado medical healing home.

sayajibichare Thursday, January 19, 2012

Require names of NGO's in INDIA[pune] who provide free medicine on HIV/AIDS....

View More Comments

Most Popular on Medindia