Prevention, Treatment and Control of HIV Infection Novel methods are under investigation: Soluble form of CD4 has been made by recombinant DNA techniques and is being studied as a viral blocking agent. As CD4 is the HIV receptor on cells, soluble CD4 may inhibit HIV from infecting cells; may block gp120-mediated events, such as cell fusions and may serve as a targeting signal to direct cytotoxic agents to HIV-infected cells. Gene therapy approach are being developed that are designed to achieve "intracellular immunization," ie., genetically alter target cells to make them resistant to HIV. Published on Sep 08, 2014Last Updated on Dec 30, 2019