What are the Symptoms and Signs of Nephrotoxicity?The Symptoms & signs of damage done to the kidney due to the drugs include:Shortness of breathExcessive fatigueNausea Pain or pressure in chestRetention of fluid, causing swelling in legs, ankles and feetDecreased urine outputIrregular heartbeat References:Drug-Induced Nephrotoxicity - (https://www.aafp.org/afp/2008/0915/p743.html)Drug-induced Kidney Diseases - (http://www.japi.org/october2003/R-970.pdf)Drug-Induced Nephrotoxicity and Its Biomarkers - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794522/)Drug-induced renal disorders - (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594214/)Pharmacology behind Common Drug Nephrotoxicities - (https://cjasn.asnjournals.org/content/early/2018/04/04/CJN.00150118)Nephrotoxicity and Renal Pathophysiology: A Contemporary Perspective - (https://www.ncbi.nlm.nih.gov/pubmed/29939355)Diagnosis, Treatment, and Prevention of Nephrotoxicity of Cancer Therapeutic Agents - (https://www.ncbi.nlm.nih.gov/books/NBK12686/) Published on Jan 03, 2019Last Updated on Jan 12, 2019