Aust J Gen Pract
The assessment and management of gamma hydroxybutyrate use in general practice.
Phan V, Arunogiri S, Lubman DI
Gamma hydroxybutyrate (GHB) is an illicit drug commonly used in music festival, party and 'chemsex' settings. Most people who use GHB do so occasional ...
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Source: PubMed
Ther Innov Regul Sci
Efficient Design of Integrated and Adaptively Interlinked Protocols for Early-Phase Drug Development Programs.
Coates S, Pohl O, Gotteland JP, Täubel J, Lorch U
Adaptive trial designs have the potential to address common challenges in drug development; they decrease timelines and costs of early drug developmen ...
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Source: PubMed
Aging Clin Exp Res 2020 Feb 01
Potential herb-drug interactions in community-dwelling older adults in China: the Shanghai Aging Study.
Chi D, Ding D, Zhao Q, Liang X, Wu W, Luo J, Wang B
Potential herb-drug interactions (pHDIs) often go unrecognized, and little is known about the prevalence of pHDIs in older adults. ...
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Source: PubMed
J. Biomol. NMR 2020 Feb 01
Mass spectrometry assisted arginine side chains assignment of NMR resonances in natural abundance proteins.
Lu J, Zhou F, Liu W, Yu F
Arginine side chains play critical roles in many protein-ligand interactions and enzyme catalysis. Unambiguous resonance assignment is a prerequisite ...
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Source: PubMed
Aging (Albany NY)
CSF1R inhibitor PLX5622 and environmental enrichment additively improve metabolic outcomes in middle-aged female mice.
Ali S, Mansour AG, Huang W, Queen NJ, Mo X, Anderson JM, Hassan Ii QN, Patel RS, Wilkins RK, Caligiuri MA, Cao L
As the elderly population grows, chronic metabolic dysfunction including obesity and diabetes are becoming increasingly common comorbidities. Hypothal ...
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Source: PubMed
