Med. Oncol.
To be or not to be: whether anti-angiogenic agent combined with immune checkpoint inhibitoris necessary in the treatment of advanced or metastatic renal cell carcinoma.
Sun L, Zhang L, Yu J, Zhou Y, Shi C, Wasan HS, Ruan S, Huang D
Although it's widely known that targeted therapy against angiogenesis and immunotherapy agents showed survival benefit over chemoradiotherapy in advan ...
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Source: PubMed
Heart Fail Rev 2020 Feb 01
Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications.
Gorabi AM, Kiaie N, Pirro M, Bianconi V, Jamialahmadi T, Sahebkar A
Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought about some beneficial effects on improving the therapeuti ...
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Source: PubMed
Cell. Mol. Life Sci. 2020 Feb 01
Thalidomide targets EGFL6 to inhibit EGFL6/PAX6 axis-driven angiogenesis in small bowel vascular malformation.
Tang CT, Zhang QW, Wu S, Tang MY, Liang Q, Lin XL, Gao YJ, Ge ZZ
Small bowel vascular malformation disease (SBVM) is the most common cause of obscure gastrointestinal bleeding (OGIB). Several studies suggested that ...
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Source: PubMed
Bioorg. Chem.
Molecular hybrid design, synthesis, in vitro and in vivo anticancer evaluation, and mechanism of action of N-acylhydrazone linked, heterobivalent ß-carbolines.
Guo L, Chen X, Chen W, Ma Q, Fan W, Zhang J, Dai B
A series of N-acylhydrazone-linked, heterobivalent ß-carboline derivatives was designed and synthesized from l-tryptophan in a nine-step reaction sequ ...
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Source: PubMed
J Ethnopharmacol 2020 Jan 30
Renshen Shouwu extract enhances neurogenesis and angiogenesis via inhibition of TLR4/NF¬?B/NLRP3 signaling pathway following ischemic stroke in rats.
Li Y, Liang W, Guo C, Chen X, Huang Y, Wang H, Song L, Zhang D, Zhan W, Lin Z, Tan H, Bei W, Guo J
Renshen Shouwu extract (RSSW) is a patented Traditional Chinese Medicine included in Chinese Pharmacopoeia for neurasthenia, forgetfulness, insomnia, ...
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Source: PubMed
