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Drug Hypersensitivity - Glossary

Last Updated on Mar 22, 2018
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Glossary

Hypersensitivity: The over-reaction of the immune system to an irritant

Allergy: A hypersensitivity of the body's immune system in response to exposure to specific substances (antigens), such as pollen, beestings, poison ivy, drugs, or foods. Anaphylactic shock is a severe form of allergy response which is a medical emergency. Symptoms of anaphylactic shock include dizziness, loss of consciousness, labored breathing, swelling of the tongue and breathing tubes, blueness of the skin, low blood pressure, and death

Diagnostic Procedure: A method used to identify a disease

Mast cells: A type of cell present in most body tissues that releases substances in response to an allergen, which causes symptoms such as inflammation

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Basophil: A type of white blood cell. Basophils are granulocytes

Anaphylaxis: Severe allergic response to a substance. Symptoms include wheezing, itching, nasal congestion, hives, immediate intense burning of hands and feet, collapse with severe drop in blood pressure, loss of consciousness and cardiac arrest. Symptoms of anaphylaxis appear within a few seconds or minutes after exposure to substance causing reaction this can be medication or herbs taken by injection, by mouth, vaginally, rectally, through a breathing apparatus or applied to skin. Anaphylaxis is an uncommon occurrence, but when it occurs, it is a SEVERE MEDICAL EMERGENCY! Without appropriate immediate treatment, it can cause death. Yell for help. Don't leave victim. Begin CPR (cardiopulmonary resuscitation), mouth-to- mouth breathing and external cardiac massage. Have someone dial "0" or 911. Don't stop CPR until help arrives.

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