What is Bubble Baby Disease?
The children can also become very sick from the weakened live viruses and bacteria present in some vaccines.
What are the Causes of Bubble Baby Disease?Bubble baby disease is inherited due to mutations in genes.
The most common form of inheritance is termed X-linked recessive. Boys are more commonly affected than girls. In this type of inheritance, the defective gene is present on the X chromosome. Boys (XY) inherit the defective gene on the X chromosome from their mothers who is a carrier (has defective gene without showing symptoms of the disease) but they suffer from the disease. Girls (XX) have one normal X chromosome and are protected from the disease and suffer from disease only if both X chromosomes carry the mutated gene.
The other form of inheritance is autosomal recessive inheritance in which both boys and girls are equally affected.
Rarely the disease affects a baby for the first time with no previous family history of the disease.