Zika virus infection is a risk factor for Guillain-Barré syndrome according to a study published by JAMA..
Guillain-Barré syndrome (GBS) is an uncommon autoimmune disorder characterized by progressive weakness and diminished deep tendon reflexes following infection or, rarely, vaccination. Increased GBS incidence has been reported in countries affected by Zika virus.
Emilio Dirlikov, Ph.D., of the Centers for Disease Control and Prevention, San Juan, Puerto Rico, and colleagues examined risk factors associated with GBS during the Zika virus epidemic in Puerto Rico.
"The pathophysiology of Zika virus infection and risk factors for developing GBS require further investigation. Clinical trials of the Zika virus vaccine should monitor for GBS. During Zika virus outbreaks, clinical suspicion should be elevated to improve GBS patient prognosis through prompt diagnosis and treatment," the authors write.