Women are more likely to suffer from asthma than men because of the absence of testosterone.

‘Before puberty boys have 1.5 times higher rate of asthma than girls, the trend reverses after puberty, when women are twice likely to have asthma as men.’

These immune cells are linked to asthma symptoms, such as inflammation and mucus production in the lungs, which causes airways to narrow during an asthma attack. 




"Initially we thought that ovarian hormones would increase inflammation, more so than testosterone making it better," said Dawn Newcomb, from the Vanderbilt University in Tennessee, the US.
"I was surprised to see that testosterone was more important in reducing inflammation," Newcomb said.
Prior studies have showed before puberty boys have approximately 1.5 times higher rate of asthma than girls. That trend reverses after puberty, when women are twice likely to have asthma as men.
This pattern continues until women hit menopause, and then the asthma rates in women start to decline, the researchers said.
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The researchers collected blood from people with and without asthma and found that those with asthma had more ILC2 cells than those without. Asthmatic women were found with more ILC2 cells than men.
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However,"sex hormones are not the only mechanism but, rather, one of many mechanisms that could be regulating airway inflammation", Newcomb said.
Source-IANS