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Woman With Male Chromosomes Delivers Twins by Invitro Fertilisation

by Julia Samuel on February 9, 2015 at 3:56 PM
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Woman With Male Chromosomes Delivers Twins by Invitro Fertilisation

Born with an infantile uterus due to genetic mutation and non-functional gonads made thirty-five-year-old woman, in Meerut, India, incapable of having a baby. Also, another shocking fact is that, she carried XY sex chromosome instead of XX chromosomes.

"This patient had a very rare intersex disorder wherein she carried XY sex chromosome pattern (46 XY), found in males instead of 46 XX chromosomes found in females", said Dr Sunil Jindal, who treated the patient.

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Dr Jindal said that the patient, a resident of Gurgaon who had been married for seven years, does not go through menstrual cycle.

"The challenge before us was to develop the uterus to a level that menstruation could take place the next bigger challenge was to develop the uterus to facilitate pregnancy", he said.
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"She was given hormonal and endocrinal treatment for six months and embryos were developed in human culture lab with donor eggs and husband's sperms," he said.

Dr Jindal said that the developing embryos were implanted in an already prepared uterus. Throughout the pregnancy period, she was kept under our observation and on Friday, she delivered twins. The babies weigh 2.5 and 2.254 kilogram and are perfectly healthy.

Source: Medindia
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