How can we modulate aging through nutrition and physical exercise? An epigenetic approach
Go to source). // The World Health Organization predicts that by 2050, 2.1 billion people worldwide will be over 60 years old, a drastic increase from only 1 billion in 2019 (2✔ ✔Trusted Source
Ageing and health
Go to source). Considering these numbers, strategies to ensure an extended “healthspan” or healthy longevity are urgently needed.
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‘A new study has explored how aging and its linked epigenetic changes may be paused through nutrition, caloric restriction and sustained physical activity.’
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In this new review, researchers Ana Teresa Rajado, Nádia Silva, Filipa Esteves, David Brito, Alexandra Binnie, Inês M. Araújo, Clévio Nóbrega, José Bragança, and Pedro Castelo-Branco from the ALFA Score Consortium, University of Algarve Campus Gambelas, William Osler Health System, and Champalimaud Centre for the Unknown discuss their present study that approaches the promotion of healthspan from an epigenetic perspective.
Epigenetics and Aging
Epigenetic phenomena are modifiable in response to an individual’s environmental exposures, and therefore link an individual’s environment to their gene expression pattern. Epigenetic studies demonstrate that aging is associated with decondensation of the chromatin, leading to an altered heterochromatin structure, which promotes the accumulation of errors.Canonical histones are replaced by histone variants, concomitant with an increase in histone post-translational modifications (PTMs). A slight increase in DNA methylation at promoters has been observed, which represses transcription of previously active genes, in parallel with global genome hypomethylation. Aging is also associated with deregulation of gene expression - usually provided by non-coding RNAs - leading to both the repression of previously transcribed genes and to the transcription of previously repressed genes.
References:
- How can we modulate aging through nutrition and physical exercise? An epigenetic approach - (https://www.aging-us.com/article/204668/text)
- Ageing and health - (https://www.who.int/news-room/fact-sheets/detail/ageing-and-health)
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Quiz on Nutrition IQ
With increasing health awareness, a lot of people are making sure that they eat nutritious food. A well-balanced diet is not only important for growing children, it is equally important for the middle-aged group as well as the elderly. But are your concepts regarding nutrition correct? Test your IQ on nutrition by taking this quiz.
With increasing health awareness, a lot of people are making sure that they eat nutritious food. A well-balanced diet is not only important for growing children, it is equally important for the middle-aged group as well as the elderly. But are your concepts regarding nutrition correct? Test your IQ on nutrition by taking this quiz.
Anti-ageing Foods
One sure approach to maintaining lasting youthful looks lies in the food that is consumed, in our daily diet. The webpage offers some great tips on preserving a wrinkle-free, glowing skin.
One sure approach to maintaining lasting youthful looks lies in the food that is consumed, in our daily diet. The webpage offers some great tips on preserving a wrinkle-free, glowing skin.
