Emerging research suggests that fluid volume swells during sleep, helping flush waste products such as amyloid-Î˛ that can precipitate disease.
A new study sheds more light on this process, finding that fluctuations in the extracellular ion composition drive those crucial fluid volume changes. In mice, manipulating the ion mix alone could wake up sleeping animals or cause active ones to nod off. Other recent papers tied insufficient flow of brain fluid more closely to sleep and disease. Alzforum explores this research in part 1 of this series.
‘Sleep helps in cleansing the brain, it is also known to be crucial in consolidating memories from the day before, but how it does this is unclear.’
Besides cleansing the brain, sleep is known to be crucial in consolidating memories from the day before, but how it does this is unclear. New research reports an essential role for a protein synthesis pathway and for specific electrical rhythms during rapid eye movement sleep, as Alzforum describes in part 2 of this series.
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