About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Vitamin E Could Help 40% of Diabetics Ward Off Heart Attacks

by Medindia Content Team on November 24, 2007 at 4:32 PM
Font : A-A+

Vitamin E Could Help 40% of Diabetics Ward Off Heart Attacks

Vitamin E supplements can significantly reduce the risk of heart attacks and related deaths for diabetics who carry a particular version of a gene, according to researchers at the Technion-Israel Institute of Technology and the Clalit Health Services in Israel.

After 18 months of treatment, people with the haptoglobin (Hp) 2-2 gene who took 400 International Units (IU) of vitamin E daily had more than 50 percent fewer heart attacks, strokes, and related deaths than Hp 2-2 patients who took a placebo pill. 40% of individuals with diabetes carry the Hp 2-2 gene.

Advertisement

The researchers will present the results on November 5 at the American Heart Meetings in Orlando, Florida. The full study will appear in the November 21 online edition of the journal Arteriosclerosis, Thrombosis, and Vascular Biology.

Most of the difference came from the reduced number of heart attacks among those taking vitamin E. In the group of 1,434 Hp 2-2 individuals taking part in the study, seven people had a heart attack, compared to 17 who did not take the vitamin. Dr. Andrew Levy, of the Technion Faculty of Medicine, said there were no side effects observed in patients who took vitamin E.
Advertisement

The study suggests that genetic testing for the Hp 2-2 gene "may be useful to identify a large group of diabetes individuals who could potentially derive cardiovascular benefit from a very inexpensive treatment," Levy said.

The finding is a new answer to an old question: can antioxidant vitamins such as vitamin E help prevent heart disease? Previously, cardiologists routinely prescribed vitamin E for their patients, but the practice has dwindled as several major studies in the past decade showed no heart-protective effects and potential harm from vitamin E mega-doses.

However, Levy and colleagues suspected that there might be one group of patients who could benefit from vitamin E: diabetic individuals with a particular variant of the haptoglobin gene. Haptoglobin is a powerful antioxidant protein that stabilizes the iron-rich red blood cell molecule called hemoglobin, preventing inflammation in the walls of arteries.

There are several versions of the haptoglobin gene. In previous studies, Levy and colleagues showed that Hp 2-2 is an inferior antioxidant compared to its genetic siblings, and that this difference is exaggerated in patients with diabetes. The researchers also discovered that diabetic patients with Hp 2-2 are two-to-three times more likely than other diabetics to suffer a cardiovascular event such as a heart attack.

"This version of the gene does not determine whether or not an individual will develop diabetes but rather whether an individual with diabetes is susceptible to developing the devastating complications associated with diabetes such as heart disease, kidney disease or visual loss," Levy noted.

A genetic test for Hp 2-2 is commercially available, said Levy, who is also a consultant for Synvista Therapeutics, which owns a patent on the use of Hp testing to predict diabetic complications. By making a kit, the group hopes to considerably lower the price of testing. According to Levy, the test would cost about $30 and only have to be done only once.

Source: Newswise
LIN/P
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Advertisement
News Category
What's New on Medindia
Coffee May Help You Fight Endometrial Cancer
Fermented Skin Care
Television Binge-Watching May Boost the Risk of Deadly Blood Clots
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Calcium and Vitamin Supplements Vitamin C / Ascorbic acid Vitamin B6 Vitamin B9 Vitamin B-12 Diabetes - Self-Monitoring of Blood Glucose (SMBG) Vitamin-F Anti-ageing and Benefits of Red Wine Cardiac Catheterization Diabetes and Exercise 

Recommended Reading
Heart Attack - Animation
Animation of Heart Attack symptoms. Heart attack is caused due to ischemia of the heart muscles ......
Vitamin B1 Deficiency Leads to Vascular Problems in Diabetics
A new research has discovered that the deficiency of thiamine, Vitamin B1, may be key to a range of ...
The Vitamin E and Heart Bonding!
Using lower levels of vitamin E supplements, such as 100 to 400 I.U. a day, have shown benefits in ....
Anti-Ageing and Benefits of Red Wine
Ageing process has always been an enigma. Recent research indicates that red wine could delay the .....
Calcium and Vitamin Supplements
Calcium and vitamin supplements are taken to provide the body with the ''required'' nutrients. Calci...
Cardiac Catheterization
Cardiac catheterization is a radiological procedure for both diagnosis and treatment of heart condit...
Diabetes - Self-Monitoring of Blood Glucose (SMBG)
Self-Monitoring Of Blood Glucose (SMBG) is one of the greatest advancements in the management of Di...
Diabetes and Exercise
Regular exercise especially in type II diabetes not only helps reduce the sugar but also reduces the...
Vitamin B-12
Vitamin B-12 is also known as cobalamine or cyanocobalamine, owing to the presence of the metal, cob...
Vitamin B6
Vitamins play an equally important part in the synthesis of neurotransmitters. Neurotransmitters in ...
Vitamin B9
Vital info about vitamin B9, its molecular structure, dietary sources, beneficial aspects, symptoms ...
Vitamin C / Ascorbic acid
Vital info about vitamin C, its molecular structure, dietary sources, beneficial aspects, symptoms o...
Vitamin-F
Essential fatty acids - omega 3 and omega 6 are sometimes referred to as Vitamin F. The body is not...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2022

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use
open close
CONSULT A DOCTOR
I have read and I do accept terms of use - Telemedicine

Advantage Medindia: FREE subscription for 'Personalised Health & Wellness website with consultation' (Value Rs.300/-)