About My Health Careers Internship MedBlogs Contact us
Medindia LOGIN REGISTER
Advertisement

Vitamin B3: Potent Modifier of Energy Metabolism

by Bidita Debnath on April 9, 2014 at 11:04 PM
Font : A-A+

 Vitamin B3: Potent Modifier of Energy Metabolism

Recently, vitamins B have been turned out to be potent modifiers of energy metabolism, especially the function of mitochondria.

Vitamin B3, (niacin) has been found to delay the signs of aging in animal models. An international collaboration between the University of Helsinki and École Polytechnique Fédérale de Lausanne reported in the high-profile journal, Embo Molecular Medicine, that vitamin B3 form, nicotinamide riboside, can slow down the progression of mitochondrial disease, suggesting its potential as a novel therapy approach to adult-onset mitochondrial muscle diseases.

Advertisement

Mitochondria power up all cells in our bodies, by generating fuel, ATP, for all cellular functions. Dysfunction of these cellular engines can cause mitochondrial disorders, which are the most common cause of inherited metabolic diseases in adults and children.

Mitochondrial myopathy is the most frequent form of adult mitochondrial disorder. The typical symptoms in the patients are muscle weakness, pain and cramps. Despite the progressive nature of these diseases, no curative treatment is available.
Advertisement

In their current publication, Dr Nahid Khan in Prof Anu Suomalainen-Wartiovaara's group showed that feeding mice with food supplemented with B3 form, nicotinamide riboside, delayed their mitochondrial myopathy. The treatment increased mitochondrial mass and function, and cured the structural abnormalities.

These results clearly showed the potential of this vitamin B form, a natural constituent of milk, to activate dysfunctional mitochondrial metabolism, Professor Wartiovaara-Suomalainen states. She continues:

These results are a breakthrough for understanding the mechanisms of human mitochondrial muscle diseases and for exploring the efficient treatment options for these progressive disorders of adults. They also highlight the potent role of niacin in guiding mitochondrial energy metabolism.

Source: Eurekalert
Advertisement

Advertisement
News A-Z
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
News Category
What's New on Medindia
Contraceptive Pills in Polycystic Ovary Syndrome (PCOS) Curtail Type 2 Diabetes Risk
Mushroom May Help Cut Down the Odds of Developing Depression
How to Battle Boredom during COVID
View all

Medindia Newsletters Subscribe to our Free Newsletters!
Terms & Conditions and Privacy Policy.

More News on:
Calcium and Vitamin Supplements Vitamin Supplements Vitamin C / Ascorbic acid Vitamin B6 Vitamin B9 Vitamin B-12 Vitamin-F Resting Metabolic Rate Undetected Nutrient Deficiencies: the Cause of Ill Health Food Combinations that Affect Your Well-being 

Recommended Reading
Folic Acid, Vitamins B6, B12 Offer No Protection from Cancer: Study
Folic acid and vitamins B6 and B12 play no significant role in preventing cancer in women at high .....
Vitamin B may Assist in Halting the Decline of Brain Function
University of California-San Francisco researchers have looked at the part played by vitamins-B-6, ....
Gulf War Illness Have Impaired Function of Mitochondria
Researchers at the UC San Diego School of Medicine have demonstrated for the first time that ......
Gulf War Illness Linked to Mitochondria Dysfunction: Study
Researchers at UC San Diego School of Medicine have found out that Gulf War illness is caused due .....
Calcium and Vitamin Supplements
Calcium and vitamin supplements are taken to provide the body with the ''required'' nutrients. Calci...
Food Combinations that Affect Your Well-Being
Combining the foods to give you the optimum nutritional value is the key to healthy eating....
Resting Metabolic Rate
Understanding how metabolic process is regulated and what factors affect the same is crucial before ...
Undetected Nutrient Deficiencies: The Cause of Ill Health
Micronutrient and antioxidant deficiencies are most common and go unnoticed. They are the root cause...
Vitamin B-12
Vitamin B-12 is also known as cobalamine or cyanocobalamine, owing to the presence of the metal, cob...
Vitamin B6
Vitamins play an equally important part in the synthesis of neurotransmitters. Neurotransmitters in ...
Vitamin B9
Vital info about vitamin B9, its molecular structure, dietary sources, beneficial aspects, symptoms ...
Vitamin C / Ascorbic acid
Vital info about vitamin C, its molecular structure, dietary sources, beneficial aspects, symptoms o...
Vitamin Supplements
Easy to understand info & tips with diagrams about vitamin supplements like vitamin C, B6, B9 & B12....
Vitamin-F
Essential fatty acids - omega 3 and omega 6 are sometimes referred to as Vitamin F. The body is not...

Disclaimer - All information and content on this site are for information and educational purposes only. The information should not be used for either diagnosis or treatment or both for any health related problem or disease. Always seek the advice of a qualified physician for medical diagnosis and treatment. Full Disclaimer

© All Rights Reserved 1997 - 2021

This site uses cookies to deliver our services. By using our site, you acknowledge that you have read and understand our Cookie Policy, Privacy Policy, and our Terms of Use